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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_4046
http://purl.obolibrary.org/obo/CHEBI_4046
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|---|---|
| Preferred Name | cyproheptadine |
| Synonyms |
ciproheptadina
Cyproheptadine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
CYPROHEPTADINE
cyproheptadinum
C21H21N
4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine
4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-ylidene}piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
cyproheptadine
4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cyproheptadine
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|---|---|
| label | cyproheptadine
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| ATCCode | R06AX02
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| Definition | The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
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| altId |
CHEBI:111005
CHEBI:605605
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| has effect |
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| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=JJCFRYNCJDLXIK-UHFFFAOYSA-N
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| is metabolised by | |
| blocks | |
| AHFScode | 04:04.92
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| Synonym |
ciproheptadina
Cyproheptadine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
CYPROHEPTADINE
cyproheptadinum
C21H21N
4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine
4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-ylidene}piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
cyproheptadine
4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
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| xref |
RxList:http://www.rxlist.com/cgi/generic2/cyprohept.htm
Guide To Pharmacology:277
ChEBI:4046
Wikipedia:http://en.wikipedia.org/wiki/Cyproheptadine
Patent:US3014911
National Drug Code Directory:49884-043-01
ChEMBL:10843226
BindingDB:50017721
CASRN:129-03-3
Wikipedia:Cyproheptadine
Drugs Product Database (DPD):2245668
KEGG DRUG:D07765
NIST Chemistry WebBook:129-03-3
PharmGKB:PA164749366
PubChem Compound:2913
IUPHAR:277
PubChem Substance:46508613
Beilstein:1348386
KEGG COMPOUND:C06935
ChemSpider:2810
Drugs.com:http://www.drugs.com/cdi/cyproheptadine.html
DrugBank:DB00434
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| CASRN | 129-03-3
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| prefixIRI | obo2:CHEBI_4046
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| SMILES |
CN1CCC(CC1)=C1C2=CC=CC=C2C=CC2=CC=CC=C12
CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
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| may interact with |
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| DBname | cyproheptadine
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| InChI | InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
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| DBBrand |
periactinol
peritol
cyproheptadiene
cyproheptadine hcl
cypoheptadine
eiproheptadine
dronactin
periactin
dibenzosuberonone/cyproheptadine
periactine
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| subClassOf |
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