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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_3749
http://purl.obolibrary.org/obo/CHEBI_3749
|
|---|---|
| Preferred Name | clofazimine |
| Synonyms |
C27H22Cl2N4
clofazimine
3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
clofazimina
3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
clofaziminum
(4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine
N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | clofazimine
|
|---|---|
| label | clofazimine
|
| DBSynonym |
chlofazimine
clofaziminum [inn-latin]
clofazimina [inn-spanish]
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| ATCCode | J04BA01
|
| Definition | 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
|
| altId | CHEBI:355347
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey |
InChIKey=WDQPAMHFFCXSNU-UHFFFAOYSA-N
InChIKey=WDQPAMHFFCXSNU-BGABXYSRSA-N
|
| is metabolised by | |
| Synonym |
C27H22Cl2N4
clofazimine
3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
clofazimina
3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
clofaziminum
(4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine
N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
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|
| xref |
ChEBI:3749
Beilstein:8168151
DrugBank:DB00845
RxList:http://www.rxlist.com/cgi/generic3/clofazimine.htm
ChEMBL:17210775
Wikipedia:http://en.wikipedia.org/wiki/Clofazimine
Drugs.com:http://www.drugs.com/cons/clofazimine.html
Patent:US2948726
CASRN:2030-63-9
ChEMBL:893291
KEGG COMPOUND:C06915
ChEMBL:3279207
PharmGKB:PA164748759
KEGG DRUG:D00278
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| CASRN | 2030-63-9
|
| prefixIRI | obo2:CHEBI_3749
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| related with | |
| SMILES |
CC(C)N=c1cc2n(-c3ccc(Cl)cc3)c3ccccc3nc2cc1Nc1ccc(Cl)cc1
CC(C)N=C1C=C2N(C3=CC=C(Cl)C=C3)C3=C(C=CC=C3)N=C2C=C1NC1=CC=C(Cl)C=C1
|
| DBname | clofazimine
|
| InChI | InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3/b30-24+
InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3
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| DBBrand |
lampren
lamprene
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| subClassOf |
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