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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_3720
http://purl.obolibrary.org/obo/CHEBI_3720
|
|---|---|
| Preferred Name | cisapride |
| Synonyms |
4-amino-5-chloro-N-{cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl}-2-methoxybenzamide
cisaprida
cis-4-amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl}-2-methoxybenzamide
cisapridum
C23H29ClFN3O4
cis-4-amino-5-chloro-N-{1-[3-(p-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl}-o-anisamide
(+-)-cisapride
4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
cis-4-amino-5-chloro-N-(1-(3-(p-fluorophenoxy)propyl)-3-methoxy-4-piperidyl)-o-anisamide
Cisapride
cisapride
4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cisapride
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|---|---|
| label | cisapride
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| ATCCode | A03FA02
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| Definition | The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
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| altId |
CHEBI:221485
CHEBI:657741
CHEBI:151790
CHEBI:143545
CHEBI:657397
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=DCSUBABJRXZOMT-IRLDBZIGSA-N
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| is metabolised by |
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| Synonym | 4-amino-5-chloro-N-{cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl}-2-methoxybenzamide
cisaprida
cis-4-amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl}-2-methoxybenzamide
cisapridum
C23H29ClFN3O4
cis-4-amino-5-chloro-N-{1-[3-(p-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl}-o-anisamide
(+-)-cisapride
4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
cis-4-amino-5-chloro-N-(1-(3-(p-fluorophenoxy)propyl)-3-methoxy-4-piperidyl)-o-anisamide
Cisapride
cisapride
4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
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| xref |
CASRN:81098-60-4
KEGG DRUG:D00274
ChEMBL:12190308
BindingDB:50005836
Patent:EP76530
ChEMBL:10891117
KEGG COMPOUND:C06910
IUPHAR:240
Guide To Pharmacology:240
ChEMBL:1995885
Drugs Product Database (DPD):2054817
ChEMBL:19110341
Patent:US4962115
Drugs.com:http://www.drugs.com/mtm/cisapride.html
ChEMBL:19663444
ChEMBL:2139471
ChEBI:3720
PharmGKB:PA449011
DrugBank:DB00604
Wikipedia:http://en.wikipedia.org/wiki/Cisapride
RxList:http://www.rxlist.com/cgi/generic/cisap.htm
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| CASRN | 81098-60-4
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| prefixIRI | obo2:CHEBI_3720
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| SMILES |
CO[C@H]1CN(CCCOC2=CC=C(F)C=C2)CC[C@H]1NC(=O)C1=CC(Cl)=C(N)C=C1OC
CO[C@H]1CN(CCCOc2ccc(F)cc2)CC[C@H]1NC(=O)c1cc(Cl)c(N)cc1OC
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| may interact with |
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| DBname | cisapride
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| InChI | InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)/t20-,22+/m1/s1
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| DBBrand |
enteropride
cipril
acenalin
pridesia
kinestase
prepulsid
propulsin
alimix
syspride
risamal
propulsid quicksolv
propulsid
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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