The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_35677 http://purl.obolibrary.org/obo/CHEBI_35677
Preferred Name	betahistine
Synonyms	2-(beta-methylaminoethyl)pyridine betahistine 2-[2-(methylamino)ethyl]pyridine N-methyl-2-pyridineethanamine betahistinum betahistina N-methyl-2-pyridin-2-ylethanamine N-methyl-2-(2-pyridinyl)ethanamine C8H12N2 methyl[2-(pyridin-2-yl)ethyl]amine [2-(2-pyridyl)ethyl]methylamine See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	betahistine
label	betahistine
ATCCode	N07CA01
Definition	An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.
has effect	http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000362 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2613 http://purl.obolibrary.org/obo/dinto_1071
activates	http://purl.obolibrary.org/obo/dinto_1071
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_71173
InChIKey	InChIKey=UUQMNUMQCIQDMZ-UHFFFAOYSA-N
blocks	http://purl.obolibrary.org/obo/dinto_2613
AHFScode	92:00.00
Synonym	2-(beta-methylaminoethyl)pyridine betahistine 2-[2-(methylamino)ethyl]pyridine N-methyl-2-pyridineethanamine betahistinum betahistina N-methyl-2-pyridin-2-ylethanamine N-methyl-2-(2-pyridinyl)ethanamine C8H12N2 methyl[2-(pyridin-2-yl)ethyl]amine [2-(2-pyridyl)ethyl]methylamine See more See less
xref	ChemSpider:2276 PharmGKB:PA165958372 Wikipedia:Betahistine CiteXplore:7589314 CASRN:5638-76-6 CiteXplore:22365373 PubChem Compound:2366 KEGG DRUG:D07522 NIST Chemistry WebBook:5638-76-6 PubChem Substance:99443252 HMDB:HMDB15644 Beilstein:112294 Wikipedia:http://en.wikipedia.org/wiki/Betahistine Reaxys:112294 CiteXplore:20530654 ChEMBL:132459 DrugBank:DB06698 ChEBI:35677 CiteXplore:22745706 See more See less
CASRN	5638-76-6
prefixIRI	obo2:CHEBI_35677
SMILES	CNCCc1ccccn1 CNCCC1=CC=CC=N1
DBname	betahistine
InChI	InChI=1S/C8H12N2/c1-9-7-5-8-4-2-3-6-10-8/h2-4,6,9H,5,7H2,1H3
DBBrand	serc
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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