The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_3213 http://purl.obolibrary.org/obo/CHEBI_3213
Preferred Name	bumetanide
Synonyms	3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid bumetanidum bumetanide 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid 3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid C17H20N2O5S bumetanida 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	bumetanide
label	bumetanide
DBSynonym	bumetanida [inn-spanish] bumetanidum [inn-latin]
ATCCode	C03CA02
Definition	4-Phenoxybenzoic acid in which the hydrogens ortho to the phenoxy group are substituted by butylamino and sulfamoyl groups. Bumetanide is a diuretic, and is used for treatment of oedema associated with congestive heart failure, hepatic and renal disease.
altId	CHEBI:239281
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000586 http://purl.obolibrary.org/obo/OAE_0000494 http://purl.obolibrary.org/obo/OAE_0001135 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_4037 http://purl.obolibrary.org/obo/dinto_1007 http://purl.obolibrary.org/obo/dinto_1147 http://purl.obolibrary.org/obo/dinto_0231
induces	http://purl.obolibrary.org/obo/dinto_2116
inhibits	http://purl.obolibrary.org/obo/dinto_1974 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_4037 http://purl.obolibrary.org/obo/dinto_1007 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_1147 http://purl.obolibrary.org/obo/dinto_0231 http://purl.obolibrary.org/obo/dinto_0520 See more See less
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35498
InChIKey	InChIKey=MAEIEVLCKWDQJH-UHFFFAOYSA-N
blocks	http://purl.obolibrary.org/obo/dinto_0341
AHFScode	40:28.08
Synonym	3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid bumetanidum bumetanide 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid 3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid C17H20N2O5S bumetanida 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid See more See less
xref	ChemSpider:2377 ChEBI:3213 ChEMBL:18374572 CASRN:28395-03-1 Patent:DE1964504 Patent:US3806534 PharmGKB:PA448682 BindingDB:25903 Drugs.com:http://www.drugs.com/cdi/bumetanide.html PubChem Substance:46508147 Beilstein:2185351 ChEMBL:3989818 Wikipedia:http://en.wikipedia.org/wiki/Bumetanide Drugs Product Database (DPD):728284 DrugBank:DB00887 Wikipedia:Bumetanide PubChem Compound:2471 National Drug Code Directory:0004-0125-01 RxList:http://www.rxlist.com/cgi/generic2/bumetan.htm KEGG DRUG:D00247 Patent:DE1964503 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/bum1058.shtml See more See less
CASRN	28395-03-1
prefixIRI	obo2:CHEBI_3213
is transported by	http://purl.obolibrary.org/obo/dinto_1974 http://purl.obolibrary.org/obo/dinto_1987
SMILES	CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O CCCCNc1cc(cc(c1Oc1ccccc1)S(N)(=O)=O)C(O)=O
may interact with	http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/CHEBI_9352 http://purl.obolibrary.org/obo/CHEBI_49662 http://purl.obolibrary.org/obo/CHEBI_31468 http://purl.obolibrary.org/obo/dinto_DB01172 http://purl.obolibrary.org/obo/CHEBI_5855 http://purl.obolibrary.org/obo/CHEBI_59594 http://purl.obolibrary.org/obo/dinto_DB00798 http://purl.obolibrary.org/obo/CHEBI_17076 http://purl.obolibrary.org/obo/dinto_DB00955 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00684 http://purl.obolibrary.org/obo/dinto_DB01404 http://purl.obolibrary.org/obo/dinto_DB01396 http://purl.obolibrary.org/obo/CHEBI_2637 http://purl.obolibrary.org/obo/CHEBI_27899 See more See less
DBname	bumetanide
InChI	InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
DBBrand	fordiuran burine fontego lunetoron segurex burinex lixil bumex See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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