The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_3172 http://purl.obolibrary.org/obo/CHEBI_3172
Preferred Name	bretylium
Synonyms	N-(2-bromobenzyl)-N,N-dimethylethanaminium 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium (2-bromobenzyl)ethyldimethylaminium [(2-bromophenyl)methyl](ethyl)dimethylazanium C11H17BrN
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	bretylium
label	bretylium
DBSynonym	bretylium tolsylate bretylium tosylate bretylate bretylum
ATCCode	C01BD02
Definition	A quaternary ammonium cation having 2-bromobenzyl, ethyl and two methyl groups attached to the nitrogen. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000345 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2664
inhibits	http://purl.obolibrary.org/obo/dinto_2664
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_37887 http://purl.obolibrary.org/obo/CHEBI_35674
InChIKey	InChIKey=AAQOQKQBGPPFNS-UHFFFAOYSA-N
AHFScode	24:04.04.20
Synonym	N-(2-bromobenzyl)-N,N-dimethylethanaminium 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium (2-bromobenzyl)ethyldimethylaminium [(2-bromophenyl)methyl](ethyl)dimethylazanium C11H17BrN See more See less
xref	RxList:http://www.rxlist.com/cgi/generic3/bretosy.htm Drugs Product Database (DPD):2185377 CASRN:59-41-6 PubChem Compound:2431 Beilstein:4135284 PharmGKB:PA448662 DrugBank:DB01158 PubChem Substance:46505320 Wikipedia:Bretylium KEGG COMPOUND:C06855 ChEMBL:773030 Wikipedia:http://en.wikipedia.org/wiki/Bretylium ChEBI:3172 ChemSpider:2337 See more See less
CASRN	59-41-6
prefixIRI	obo2:CHEBI_3172
SMILES	CC[N+](C)(C)CC1=CC=CC=C1Br CC[N+](C)(C)Cc1ccccc1Br
may interact with	http://purl.obolibrary.org/obo/CHEBI_5280 http://purl.obolibrary.org/obo/dinto_DB00243 http://purl.obolibrary.org/obo/CHEBI_63611 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/CHEBI_63598 http://purl.obolibrary.org/obo/dinto_DB00365 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/dinto_DB00976 See more See less
DBname	bretylium
InChI	InChI=1S/C11H17BrN/c1-4-13(2,3)9-10-7-5-6-8-11(10)12/h5-8H,4,9H2,1-3H3/q+1
DBBrand	darentin bretylol bretylan darenthin ornid
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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