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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_2972
http://purl.obolibrary.org/obo/CHEBI_2972
|
|---|---|
| Preferred Name | baclofen |
| Synonyms |
baclofenum
beta-(Aminomethyl)-p-chlorohydrocinnamic acid
C10H12ClNO2
beta-(4-Chlorophenyl)gaba
(+-)-Baclofen
DL-Baclofen
DL-4-Amino-3-p-chlorophenylbutanoic acid
baclofene
baclofeno
4-Amino-3-(4-chlorophenyl)butyric acid
beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
beta-(p-Chlorophenyl)-gamma-aminobutyric acid
gamma-Amino-beta-(p-chlorophenyl)butyric acid
baclofen
4-amino-3-(4-chlorophenyl)butanoic acid
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | baclofen
|
|---|---|
| label | baclofen
|
| ATCCode | M03BX01
|
| Definition | A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant.
|
| has effect |
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=KPYSYYIEGFHWSV-UHFFFAOYSA-N
|
| AHFScode | 12:20.12
|
| Synonym |
baclofenum
beta-(Aminomethyl)-p-chlorohydrocinnamic acid
C10H12ClNO2
beta-(4-Chlorophenyl)gaba
(+-)-Baclofen
DL-Baclofen
DL-4-Amino-3-p-chlorophenylbutanoic acid
baclofene
baclofeno
4-Amino-3-(4-chlorophenyl)butyric acid
beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
beta-(p-Chlorophenyl)-gamma-aminobutyric acid
gamma-Amino-beta-(p-chlorophenyl)butyric acid
baclofen
4-amino-3-(4-chlorophenyl)butanoic acid
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|
| xref |
Drugs.com:http://www.drugs.com/baclofen.html
PubChem Compound:2284
Wikipedia:http://en.wikipedia.org/wiki/Baclofen
Beilstein:2104494
ChemSpider:2197
Guide To Pharmacology:1084
Patent:NL6407755
DrugBank:DB00181
Drugs Product Database (DPD):2242151
ChEMBL:132869
ChEBI:2972
BindingDB:24182
KEGG DRUG:D00241
IUPHAR:1084
RxList:http://www.rxlist.com/cgi/generic/baclofen.htm
PharmGKB:PA448533
Wikipedia:Baclofen
CASRN:1134-47-0
Patent:US3471548
National Drug Code Directory:0091-3351-01
PubChem Substance:46508181
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|
| CASRN | 1134-47-0
|
| prefixIRI | obo2:CHEBI_2972
|
| SMILES |
NCC(CC(O)=O)c1ccc(Cl)cc1
NCC(CC(O)=O)C1=CC=C(Cl)C=C1
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| may interact with | |
| DBname | baclofen
|
| InChI | InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
|
| DBBrand |
nu-baclofen
pms-baclofen
lioresal intrathecal
baclon
kemstro
lioresal
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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