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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_291342
http://purl.obolibrary.org/obo/CHEBI_291342
|
|---|---|
| Preferred Name | desloratadine |
| Synonyms |
descarboethoxyloratadine
DESLORATADINE
8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
desloratadine
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaene
C19H19ClN2
8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | desloratadine
|
|---|---|
| label | desloratadine
|
| DBSynonym |
descarboethoxyloratadine
desloratidine
descarboethoxyoratidine
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| ATCCode | R06AX27
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| Definition | Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=JAUOIFJMECXRGI-UHFFFAOYSA-N
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| blocks | |
| AHFScode | 04:08.00
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| Synonym |
descarboethoxyloratadine
DESLORATADINE
8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
desloratadine
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaene
C19H19ClN2
8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
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|
| xref |
Drugs Product Database (DPD):2243919
Wikipedia:http://en.wikipedia.org/wiki/Desloratadine
ChemSpider:110575
ChEMBL:15482930
PubChem Substance:46507996
CASRN:100643-71-8
Wikipedia:Desloratadine
PharmGKB:PA164776964
Patent:EP208855
ChEMBL:9934454
Beilstein:4263164
DrugBank:DB00967
RxList:http://www.rxlist.com/cgi/generic3/clarinex.htm
ChEBI:291342
PubChem Compound:124087
BindingDB:50073179
Drugs.com:http://www.drugs.com/cdi/desloratadine.html
National Drug Code Directory:0085-1264-01
Patent:US4659716
ChEMBL:11844681
KEGG DRUG:D03693
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| CASRN | 100643-71-8
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| prefixIRI | obo2:CHEBI_291342
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| SMILES |
Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1
ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1
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| may interact with | |
| DBname | desloratadine
|
| InChI | InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
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| DBBrand |
claramax
clarinex reditabs
aerius
neoclarityn
clarinex
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| subClassOf |
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