The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_28177 http://purl.obolibrary.org/obo/CHEBI_28177
Preferred Name	theophylline
Synonyms	C7H8N4O2 Respbid 1,3-Dimethylxanthine Theolair 1,3-dimethyl-7H-purine-2,6-dione 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione Theophylline Theo-Dur theophylline anhydrous THEOPHYLLINE Elixophyllin 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Theophyllin Uniphyl theophylline See more See less
Type	http://www.w3.org/2002/07/owl#Class

label	theophylline
prefLabel	theophylline
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_1221 See more See less
blocks	http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_0932 http://purl.obolibrary.org/obo/dinto_2164
Definition	A dimethylxanthine having the two methyl groups located at positions 1 and 3.
DBBrand	uniphyl accurbron slo-phyllin theobid teofyllamin somophyllin crt optiphyllin teolair theochron t-phyl chronophyllin theolair pulmidur sustaire pro-vent choledyl sa diffumal euphylong uniphyllin maphylline solosin bronkodyl bronchoretard theoplus tesona theacitin theobid jr. somophyllin-df theoclear 80 unifyl theodel quibron acet-theocin liquorice elixophyllin sr respicur telb-ds theograd theocontin aerolate theopek slo-bid asbron nuelin theospan egifilin teonova theo-sav spophyllin retard afonilum talotren respid elixex theolixir lasma afonilm quibron t/sr teocen 200 quibron t pulmo-timelets diphyllin aerolate iii theoclear-80 bilordyl theolix labid telbans dry syrup respbid bronkodyl sr theostat 80 doraphyllin theotard asmalix dyspne-inhal theo-nite constant t theofol physpan liquophylline etheophyl theoclear la elixophylline somophyllin-t duraphyl theodrip theoclear uni-dur parkophyllin lanophyllin theobid duracap theoclear-200 theophyl-sr euphyllin asmax theophylline-sr synophylate teosona theovent theolair-sr theoclear l.a.-130 tefamin theophyl-225 theo-24 aerobin cetraphylline xanthium elixomin theo-ds unilong somophyllin-crt theal tablets elixicon armophylline teofilina elixophyllin theo-dur theona p medaphyllin theo-11 duraphyllin theo 24 austyn aquaphyllin aerolate sr xantivent synophylate-l.a. cenules quibron-t theophyl theostat elan somophyllin t quibron-t/sr theocin theodur dry syrup theoclair-sr euphylline See more See less
ATCCode	R03DA04 R03DA05
modulates	http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_0932 http://purl.obolibrary.org/obo/dinto_2164
SMILES	CN1C2=C(NC=N2)C(=O)N(C)C1=O Cn1c2nc[nH]c2c(=O)n(C)c1=O
InChI	InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
CASRN	58-55-9
prefixIRI	obo2:CHEBI_28177
altId	CHEBI:45950 CHEBI:9523 CHEBI:26940
Synonym	C7H8N4O2 Respbid 1,3-Dimethylxanthine Theolair 1,3-dimethyl-7H-purine-2,6-dione 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione Theophylline Theo-Dur theophylline anhydrous THEOPHYLLINE Elixophyllin 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Theophyllin Uniphyl theophylline See more See less
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001505 http://purl.obolibrary.org/obo/OAE_0000817 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001437 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001393 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001378 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0001044 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
binds	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1637 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_3662 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_1014 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_3000 http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_0932 http://purl.obolibrary.org/obo/dinto_2164 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_1221 See more See less
has role	http://purl.obolibrary.org/obo/CHEBI_50846 http://purl.obolibrary.org/obo/CHEBI_51371 http://purl.obolibrary.org/obo/CHEBI_71232 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_50218 http://purl.obolibrary.org/obo/CHEBI_67079 http://purl.obolibrary.org/obo/CHEBI_35523 http://purl.obolibrary.org/obo/CHEBI_49167 See more See less
DBname	theophylline
InChIKey	InChIKey=ZFXYFBGIUFBOJW-UHFFFAOYSA-N
subClassOf	http://purl.obolibrary.org/obo/dinto_000055
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_102524 http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_157175 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_10100 http://purl.obolibrary.org/obo/dinto_DB00822 http://purl.obolibrary.org/obo/CHEBI_3437 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/dinto_DB00306 http://purl.obolibrary.org/obo/CHEBI_16335 http://purl.obolibrary.org/obo/CHEBI_4888 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/dinto_DB01355 http://purl.obolibrary.org/obo/dinto_DB00806 http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_102216 http://purl.obolibrary.org/obo/CHEBI_5615 http://purl.obolibrary.org/obo/dinto_DB00231 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/dinto_DB00532 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB01336 http://purl.obolibrary.org/obo/CHEBI_2453 http://purl.obolibrary.org/obo/dinto_DB00312 http://purl.obolibrary.org/obo/dinto_DB01226 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/dinto_DB01354 http://purl.obolibrary.org/obo/dinto_DB01323 http://purl.obolibrary.org/obo/dinto_DB00034 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00237 http://purl.obolibrary.org/obo/dinto_DB00105 http://purl.obolibrary.org/obo/dinto_DB01558 http://purl.obolibrary.org/obo/dinto_DB01361 http://purl.obolibrary.org/obo/dinto_DB01352 http://purl.obolibrary.org/obo/dinto_DB00365 http://purl.obolibrary.org/obo/CHEBI_8887 http://purl.obolibrary.org/obo/CHEBI_6916 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_100241 http://purl.obolibrary.org/obo/CHEBI_100246 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_6758 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_3387 http://purl.obolibrary.org/obo/CHEBI_10112 http://purl.obolibrary.org/obo/CHEBI_8466 http://purl.obolibrary.org/obo/CHEBI_7907 http://purl.obolibrary.org/obo/CHEBI_9774 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/CHEBI_2914 http://purl.obolibrary.org/obo/CHEBI_63628 http://purl.obolibrary.org/obo/dinto_DB01351 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/CHEBI_50199 http://purl.obolibrary.org/obo/CHEBI_9588 http://purl.obolibrary.org/obo/CHEBI_45979 http://purl.obolibrary.org/obo/dinto_DB06213 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/CHEBI_31739 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_4707 http://purl.obolibrary.org/obo/dinto_DB01346 http://purl.obolibrary.org/obo/dinto_DB01353 http://purl.obolibrary.org/obo/dinto_DB01341 http://purl.obolibrary.org/obo/CHEBI_9073 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/dinto_DB00951 See more See less
inhibits	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1637 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_3662 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_1014 http://purl.obolibrary.org/obo/dinto_0074 See more See less
related with	http://purl.obolibrary.org/obo/dinto_3000
induces	http://purl.obolibrary.org/obo/dinto_3662
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_1221 See more See less
type	http://www.w3.org/2002/07/owl#Class
xref	CiteXplore:18307508 CiteXplore:16651698 CiteXplore:10921764 CiteXplore:10796631 CiteXplore:11200776 CiteXplore:22771369 Drugs Product Database (DPD):627410 CiteXplore:21796703 CiteXplore:8960878 CiteXplore:15317832 RxList:http://www.rxlist.com/cgi/generic/theosr.htm CiteXplore:16083514 Beilstein:13463 KEGG COMPOUND:C07130 National Drug Code Directory:0089-0342-10 CiteXplore:22981724 BindingDB:10847 Guide To Pharmacology:413 CiteXplore:7389811 CiteXplore:11170036 PharmGKB:PA451647 CiteXplore:19727789 Reaxys:13463 Wikipedia:http://en.wikipedia.org/wiki/Theophylline CiteXplore:15902964 CiteXplore:8730732 CASRN:58-55-9 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/the1440.shtml CiteXplore:10836323 Wikipedia:Theophylline CiteXplore:21467671 CiteXplore:11950649 CiteXplore:19888960 CiteXplore:7767539 CiteXplore:11848250 CiteXplore:11126990 CiteXplore:22915350 PubChem Substance:46505949 PDBeChem:TEP CiteXplore:12836095 CiteXplore:11261527 ChEMBL:481693 DrugBank:DB00277 CiteXplore:15356646 CiteXplore:22377744 CiteXplore:15829161 CiteXplore:15202575 CiteXplore:22770225 CiteXplore:17207928 HMDB:HMDB01889 CiteXplore:15005370 CiteXplore:19559058 CiteXplore:15908149 CiteXplore:7656958 ChEBI:28177 ChemSpider:2068 Drugs.com:http://www.drugs.com/cdi/theophylline.html CiteXplore:11941393 CiteXplore:11826912 CiteXplore:14988770 CiteXplore:22702215 CiteXplore:14713563 CiteXplore:22836872 PDB:TEP CiteXplore:15042504 CiteXplore:7302609 KEGG DRUG:D00371 Gmelin:51226 PubChem Compound:2153 CiteXplore:22541679 CiteXplore:18800032 CiteXplore:21834615 CiteXplore:22541837 CiteXplore:11408152 CiteXplore:16930490 NIST Chemistry WebBook:58-55-9 CiteXplore:9256615 CiteXplore:15483348 CiteXplore:15739418 CiteXplore:19845735 CiteXplore:14517178 IUPHAR:413 MetaCyc:CPD-12479 CiteXplore:22909172 CiteXplore:12531775 CiteXplore:17130682 CiteXplore:11949272 CiteXplore:10893702 See more See less
DBSynonym	theophylline aminoacetate dimethylxanthine theophyllin theophylline anhydrous theophyline pseudotheophylline See more See less
AHFScode	86:16.00
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_1637 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_1014 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_0932 http://purl.obolibrary.org/obo/dinto_3000 http://purl.obolibrary.org/obo/dinto_2164 See more See less

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