The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/CHEBI_2668
http://purl.obolibrary.org/obo/CHEBI_2668
Preferred Name

amlodipine
Synonyms
amlodipinum
amlodipino
C20H25ClN2O5
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
amlodipine
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Amlodipine Free Base
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
amlodipine
label
amlodipine
DBSynonym
amlodipine besilate
amlodipinum [latin]
amlodipino [spanish]
amlodipine free base
amlodipine besylate
amlodipine benzenesulfonate
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ATCCode
C08CA01
Definition
A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
has pharmacological target
inhibits
type
has role
InChIKey
InChIKey=HTIQEAQVCYTUBX-UHFFFAOYSA-N
is metabolised by
AHFScode
24:28.08
Synonym
amlodipinum
amlodipino
C20H25ClN2O5
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
amlodipine
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Amlodipine Free Base
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xref
CiteXplore:16422032
PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam
CiteXplore:8310973
Wikipedia:Amlodipine
CiteXplore:21591999
CiteXplore:9156957
PubChem Substance:46507214
CASRN:88150-42-9
Reaxys:3570229
Wikipedia:http://en.wikipedia.org/wiki/Amlodipine
CiteXplore:19450066
Patent:US4572909
ChEMBL:518414
National Drug Code Directory:53808-0200-1
CiteXplore:1532771
Beilstein:3570229
DrugBank:88150-42-9
KEGG COMPOUND:C06825
ChemSpider:2077
Drugs Product Database (DPD):878936
RxList:http://www.rxlist.com/cgi/generic/amlod2.htm
PubChem Compound:2162
CiteXplore:1834846
ChEBI:2668
CiteXplore:7522286
Patent:EP89167
PharmGKB:PA448388
KEGG DRUG:D07450
CiteXplore:8310972
DrugBank:DB00381
Drugs.com:http://www.drugs.com/amlodipine.html
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CASRN
88150-42-9
prefixIRI
obo2:CHEBI_2668
SMILES
CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC
may interact with
DBname
amlodipine
InChI
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
DBBrand
lipinox
amvaz
coroval
norvasc
amlodis
amlocard
lotrel
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subClassOf
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