The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/CHEBI_251408
http://purl.obolibrary.org/obo/CHEBI_251408
Preferred Name

edrophonium
Synonyms
N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium
Edrophonium
Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium
N-ethyl-3-hydroxy-N,N-dimethylanilinium
C10H16NO
EDROPHONIUM ION
edrophonium
(3-hydroxyphenyl)dimethylethylammonium
EDROPHONIUM
3-hydroxy-N,N-dimethyl-N-ethylanilinium
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
edrophonium
label
edrophonium
DBSynonym
edrophone chloride
edrophonum
edr
edrophonium ion
edrophonium chloride
Definition
N-Ethyl-N,N-dimethylanilinium in which on of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
altId
CHEBI:42376
CHEBI:4758
has pharmacological target
inhibits
type
has role
InChIKey
InChIKey=VWLHWLSRQJQWRG-UHFFFAOYSA-O
AHFScode
36:56.00
Synonym
N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium
Edrophonium
Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium
N-ethyl-3-hydroxy-N,N-dimethylanilinium
C10H16NO
EDROPHONIUM ION
edrophonium
(3-hydroxyphenyl)dimethylethylammonium
EDROPHONIUM
3-hydroxy-N,N-dimethyl-N-ethylanilinium
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xref
CASRN:312-48-1
CiteXplore:7488499
PDB:EDR
Wikipedia:http://en.wikipedia.org/wiki/Edrophonium
PharmGKB:PA449437
ChemSpider:3090
PDBeChem:EDR
Drugs.com:http://www.drugs.com/mtm/edrophonium.html
Beilstein:3905622
DrugBank:DB01010
PubChem Compound:3202
KEGG COMPOUND:C06976
RxList:http://www.rxlist.com/cgi/generic3/edrophonium.htm
National Drug Code Directory:10019-873-15
ChEBI:251408
PubChem Substance:46507530
Drugs Product Database (DPD):2188848
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CASRN
116-38-1
prefixIRI
obo2:CHEBI_251408
SMILES
CC[N+](C)(C)c1cccc(O)c1
CC[N+](C)(C)C1=CC(O)=CC=C1
may interact with
DBname
edrophonium
InChI
InChI=1S/C10H15NO/c1-4-11(2,3)9-6-5-7-10(12)8-9/h5-8H,4H2,1-3H3/p+1
DBBrand
enlon plus
reversol
tensilon
tensilon chloride
antirex
enlon
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subClassOf
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