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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_205919
http://purl.obolibrary.org/obo/CHEBI_205919
|
|---|---|
| Preferred Name | clobetasol |
| Synonyms |
C22H28ClFO4
21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
clobetasolum
(1R,2S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
clobetasol
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | clobetasol
|
|---|---|
| label | clobetasol
|
| ATCCode | D07AD01
|
| Definition | 16beta-Methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
|
| altId | CHEBI:282071
|
| has effect |
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=FCSHDIVRCWTZOX-DVTGEIKXSA-N
|
| AHFScode | 84:06.00
|
| Synonym | C22H28ClFO4
21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
clobetasolum
(1R,2S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
clobetasol
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|
| xref |
ChEBI:205919
RxList:http://www.rxlist.com/cgi/generic/olux.htm
CASRN:25122-41-2
Patent:US3721687
DrugBank:DB01013
National Drug Code Directory:0462-0269-50
Drugs Product Database (DPD):2245524
Drugs.com:http://www.drugs.com/cdi/clobetasol-cream.html
Wikipedia:http://en.wikipedia.org/wiki/Clobetasol
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/tem1431.shtml
Beilstein:6748271
Patent:DE1902340
KEGG DRUG:D07715
PharmGKB:PA164744375
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| CASRN | 25122-46-7
|
| prefixIRI | obo2:CHEBI_205919
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| SMILES | [H][C@@]12C[C@H](C)[C@](O)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
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| may interact with | |
| DBname | clobetasol
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| InChI | InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
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| DBBrand |
clobesol
dermovate
embeline
olux
clobetasole propionate
clobetasol propionate [usan:jan]
temovate e
temovate
clobex
clobetasolpropionat mikron.
embeline e
clobetasol propionate
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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