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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_195280
http://purl.obolibrary.org/obo/CHEBI_195280
|
|---|---|
| Preferred Name | artemether |
| Synonyms |
beta-artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
artemisininelactol methyl ether
artemether
artemetero
artemetherum
10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
beta-dihydroartemisinin methyl ether
dihydroartemisinin methyl ether
C16H26O5
methyl-dihydroartemisinine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | artemether
|
|---|---|
| label | artemether
|
| DBSynonym |
sm-224
dihydroqinghaosu methyl ether
dihydroartemisinin methyl ether
|
| ATCCode | P01BE02
|
| Definition | An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.
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| induces | |
| type | |
| has role | |
| InChIKey | InChIKey=SXYIRMFQILZOAM-HVNFFKDJSA-N
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| is metabolised by | |
| AHFScode | 8:30.08
|
| Synonym | beta-artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
artemisininelactol methyl ether
artemether
artemetero
artemetherum
10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
beta-dihydroartemisinin methyl ether
dihydroartemisinin methyl ether
C16H26O5
methyl-dihydroartemisinine
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|
| xref |
ChEMBL:18243702
ChEMBL:3279208
ChEMBL:673926
PharmGKB:PA165111698
BindingDB:50022886
Wikipedia:http://en.wikipedia.org/wiki/Artemether
Beilstein:6569878
Drugs.com:http://www.drugs.com/pro/coartem.html
ChEMBL:17242150
DrugBank:DB06697
KEGG DRUG:D02483
ChEMBL:16033274
ChEMBL:11141088
ChEBI:195280
RxList:http://www.rxlist.com/coartem-drug.htm
CASRN:71963-77-4
ChEMBL:12781185
Wikipedia:Artemether
ChEMBL:17404003
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| CASRN | 71963-77-4
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| prefixIRI | obo2:CHEBI_195280
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| SMILES |
[H][C@@]12CC[C@@]3(C)OO[C@@]11[C@@]([H])(CC[C@H]2C)[C@@H](C)[C@@H](OC)O[C@]1([H])O3
[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OC)[C@@H]2C)O4
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| may interact with |
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| DBname | artemether
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| InChI | InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1
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| subClassOf |
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