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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Id | http://purl.obolibrary.org/obo/CHEBI_17650
http://purl.obolibrary.org/obo/CHEBI_17650
|
|---|---|
| Preferred Name | cortisol |
| Synonyms |
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
4-pregnen-11beta,17alpha,21-triol-3,20-dione
Reichstein's substance M
C21H30O5
Kendall's compound F
hydrocortisone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
hydrocortisonum
hidrocortisona
17-hydroxycorticosterone
11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
Cortisol
Hydrocortisone
11beta-hydrocortisone
cortisol
11beta,17,21-trihydroxypregn-4-ene-3,20-dione
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
cortisol
|
|---|---|
| prefLabel |
cortisol
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| is metabolised by | |
| is transported by | |
| Definition |
Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses
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| DBBrand |
hydro-colisona
amberin
nogenic hc
nutracort
micort-hc
hycortole
stie-cort
cort-dome
genacort
cortolotion
hytone lotion
traumaide
cutisol
proctofoam
sigmacort
cortiment
orabase hca
texacort lotion 25
prepcort
compound f
lubricort
vytone
dermolate
domolene-hc
hytisone
uniderm
algicirtis
aeroseb-hc
aquanil hc
schericur
tarcortin
alacort
derm-aid
cobadex
cortifoam
acticort
lacticare-hc
stiefcorcil
lacticare hc
aquacort
foille insetti
protocort
cortenema
hydro-adreson
neosporin-h ear
hydroskin
hycort
eldecort
texacort
drotic
cortoxide
polcort h
prevex hc
kyypakkaus
cortisolonum
flexicort
ficortril
preparation h hydrocortisone cream
transderma h
clear aid
optef
synacort
lactisona
dermocortal
pandel
hydrocortistab
hemsol-hc
maintasone
dricort
pediotic suspension
cortef
dermil
hydracort
systral hydrocort
urocortisone
westcort
cortifan
thyrotropic-releasing factor
incortin-h
h-cort
scalpicin capilar
epicort
esiderm h
locoid
zenoxone
efcortelan
vosol hc
signef
anflam
medicort
cortonema
anusol hc
cortisporin otico
ala-cort
dermaspray
hydrocortal
tetrahydro e
efcorbin
locoid lipocream
tetrahydrocompound e
hi-cor
balneol-hc
hycortol
permicort
proctocort
otobiotic
cortef acetate
heb cort
aeroseb hc
delacort
basan-corti
hytone
milliderm
epiderm h
otosone-f
hidro-colisona
cortispray
evacort
otocort
ef corlin
kendall's compound f
heb-cort
cortril
dioderm
cremesone
incortin-hydrogen
hydrasson
remederm hc
hidalone
timocort
colocort
cortisporin
meusicort
fiocortril
penecort
cetacort
eldercort
cortisol alcohol
alphaderm
cortanal
gyno-cortisone
hydrocortone
dome-cort
cleiton
nystaform-hc
cortesal
glycort
cortaid
cremicort-h
caldecort spray
cortisol
reichstein's substance m
rectoid
corticreme
dermacort
scheroson f
ala-scalp
beta-hc
barseb hc
sanatison
mildison
komed hc
efcortelin
hydrocortisyl
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|
| ATCCode |
S02BA01
D07AC16
S01BA02
D07AB02
D07AB11
A01AC03
A07EA02
H02AB09
D07AA02
C05AA01
D07XA01
S01CB03
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|
| modulates | |
| SMILES |
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
|
| InChI |
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
|
| CASRN |
50-23-7
|
| prefixIRI |
obo2:CHEBI_17650
|
| altId |
CHEBI:24633
CHEBI:58221
CHEBI:3893
CHEBI:14023
|
| Synonym |
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
4-pregnen-11beta,17alpha,21-triol-3,20-dione
Reichstein's substance M
C21H30O5
Kendall's compound F
hydrocortisone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
hydrocortisonum
hidrocortisona
17-hydroxycorticosterone
11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
Cortisol
Hydrocortisone
11beta-hydrocortisone
cortisol
11beta,17,21-trihydroxypregn-4-ene-3,20-dione
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|
| has effect |
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|
| binds |
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|
| has role | |
| DBname |
hydrocortisone
|
| InChIKey |
InChIKey=JYGXADMDTFJGBT-VWUMJDOOSA-N
|
| subClassOf | |
| may interact with |
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|
| inhibits | |
| related with | |
| induces | |
| is substrate of | |
| type | |
| xref |
NIST Chemistry WebBook:50-23-7
Drugs Product Database (DPD):2242930
National Drug Code Directory:0009-0142-01
DrugBank:DB00741
PDB:PDN
KEGG COMPOUND:C00735
LIPID MAPS:LMST02030001
Beilstein:1354819
Guide To Pharmacology:2868
ChemSpider:5551
KEGG DRUG:D00088
PubChem Substance:46505089
CASRN:50-23-7
ChEBI:17650
Drugs.com:http://www.drugs.com/cdi/hydrocortisone.html
IUPHAR:2868
PubChem Compound:5754
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/hyd1199.shtml
Wikipedia:http://en.wikipedia.org/wiki/Hydrocortisone
PharmGKB:PA449905
RxList:http://www.rxlist.com/cgi/generic/hydrocortisone.htm
ChEMBL:474052
CiteXplore:10438974
Patent:US2602769
Wikipedia:Hydrocortisone
BindingDB:22476
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|
| DBSynonym |
hydrocortisone sodium phosphate
hydrocortisone base
hydrocortisonum [inn-latin]
idrocortisone [dcit]
hydrocortisone free alcohol
11beta-hydroxycortisone
hydrocorticosterone
hydrocortisone acetate
hydroxycortisone
dihydrocostisone
hydrocortisone alcohol
hydrocortisone valerate
17alpha-hydroxycorticosterone
hidrocortisona [inn-spanish]
anti-inflammatory hormone
hydrocortisone butyrate
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|
| activates | |
| AHFScode |
84:06.00
52:08.08
68:04.00
|
| has pharmacological target |
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