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The Drug-Drug Interactions Ontology
| Preferred Name | codeine | |
| Synonyms |
morphine-3-methyl ether codeina codeine anhydrous C18H21NO3 methylmorphine (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol l-codeine codeine 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-ol Codeine morphine 3-methyl ether morphine monomethyl ether Coducept Codicept Codein 3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol O(3)-methylmorphine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_16714 |
|
| activates | ||
| AHFScode |
28:08.08 48:08.00
|
|
| altId |
CHEBI:23348 CHEBI:3803 CHEBI:14006
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|
| ATCCode |
R05DA12 N02AA08 R05DA04
|
|
| binds |
http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960 http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_1850 http://purl.obolibrary.org/obo/dinto_0901 |
|
| CASRN |
76-57-3
|
|
| DBBrand |
codeine contin
|
|
| DBname |
codeine
|
|
| DBSalt |
codeine sulfate codeine phosphate
|
|
| DBSynonym |
codeine anhydrous methylmorphine l-codeine norcodeine, n-methyl morphine monomethyl ether norcodine, n-methyl
|
|
| Definition |
Codeine is an alkaloid found in the opium poppy, Papaver somniferum var. album; has analgesic, anti-tussive and anti-diarrhoeal properties.
|
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000396 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0760 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_60606 |
|
| InChI |
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
|
|
| InChIKey |
InChIKey=OROGSEYTTFOCAN-DNJOTXNNSA-N
|
|
| inhibits | ||
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_1850 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_1850 http://purl.obolibrary.org/obo/dinto_0901 |
|
| is transported by | ||
| label |
codeine
|
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/dinto_DB01346 |
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_16714
|
|
| prefLabel |
codeine
|
|
| related with | ||
| SMILES |
[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O [H][C@]12C=C[C@H](O)[C@@H]3Oc4c(OC)ccc5C[C@H]1N(C)CC[C@@]23c45
|
|
| Synonym |
morphine-3-methyl ether codeina codeine anhydrous C18H21NO3 methylmorphine (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol l-codeine codeine 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-ol Codeine morphine 3-methyl ether morphine monomethyl ether Coducept Codicept Codein 3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol O(3)-methylmorphine
|
|
| xref |
KEGG COMPOUND:C06174 Wikipedia:http://en.wikipedia.org/wiki/Codeine Wikipedia:Codeine CiteXplore:2215478 RxList:http://www.rxlist.com/cgi/generic/codphos.htm Beilstein:5303198 Drugs.com:http://www.drugs.com/cdi/codeine-phosphate-soluble-tablets.html ChEBI:16714 National Drug Code Directory:54868-2541-0 PharmGKB:PA449088 Beilstein:5768734 ChemSpider:4447447 Drugs Product Database (DPD):593451 CASRN:76-57-3 DrugBank:DB00318 PubChem Substance:46507764 Gmelin:232454 NIST Chemistry WebBook:76-57-3 Beilstein:94996 ChEMBL:106167 PubChem Compound:5284371
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| subClassOf |
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