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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_149836
http://purl.obolibrary.org/obo/CHEBI_149836
|
|---|---|
| Preferred Name | tigecycline |
| Synonyms |
C29H39N5O8
(4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | tigecycline
|
|---|---|
| label | tigecycline
|
| DBSynonym |
gar-936
way-gar-936
gar-936,tigecycline
|
| ATCCode | J01AA12
|
| Definition | Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms.
|
| altId |
CHEBI:473970
CHEBI:29696
|
| has effect |
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| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=FPZLLRFZJZRHSY-HJYUBDRYSA-N
|
| AHFScode | 08:12.24
|
| Synonym | C29H39N5O8
(4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
|
| xref |
KEGG COMPOUND:C12012
ChemSpider:4445273
ChEBI:149836
KEGG DRUG:D01079
PharmGKB:PA164746412
Reaxys:8379453
ChEMBL:17220399
DrugBank:DB00560
ChEMBL:17353249
CASRN:220620-09-7
Wikipedia:http://en.wikipedia.org/wiki/Tigecycline
RxList:http://www.rxlist.com/cgi/generic4/tygacil.htm
ChEMBL:17210772
PubChem Compound:5282044
Drugs.com:http://www.drugs.com/cdi/tigecycline.html
ChEMBL:17194827
ChEMBL:17307973
ChEMBL:17353238
PubChem Substance:46509041
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| CASRN | 220620-09-7
|
| prefixIRI | obo2:CHEBI_149836
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| related with | |
| SMILES | [H][C@@]12CC3=C(C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C
[H][C@@]12Cc3c(cc(NC(=O)CNC(C)(C)C)c(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C
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| may interact with | |
| DBname | tigecycline
|
| InChI | InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
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| DBBrand | tygacil
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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