Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_126598
http://purl.obolibrary.org/obo/CHEBI_126598
|
|---|---|
| Preferred Name | cinalukast |
| Synonyms |
4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
C23H28N2O3S
cinalukast
3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cinalukast
|
|---|---|
| label | cinalukast
|
| Definition | 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.
|
| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=BZMKNPGKXJAIDV-VAWYXSNFSA-N
|
| blocks | |
| Synonym |
4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
C23H28N2O3S
cinalukast
3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
|
| xref |
PubChem Substance:46505799
PharmGKB:PA164743057
PubChem Compound:6436135
BindingDB:50064086
KEGG DRUG:D02846
ChEBI:126598
CASRN:128312-51-6
ChemSpider:4940804
DrugBank:DB00587
See more
See less
|
| CASRN | 128312-51-6
|
| prefixIRI | obo2:CHEBI_126598
|
| SMILES |
CCC(CC)(CC(=O)NC1=CC=CC(\C=C\C2=NC(=CS2)C2CCC2)=C1)C(O)=O
CCC(CC)(CC(=O)Nc1cccc(\\C=C\\c2nc(cs2)C2CCC2)c1)C(O)=O
|
| DBname | cinalukast
|
| InChI | InChI=1S/C23H28N2O3S/c1-3-23(4-2,22(27)28)14-20(26)24-18-10-5-7-16(13-18)11-12-21-25-19(15-29-21)17-8-6-9-17/h5,7,10-13,15,17H,3-4,6,8-9,14H2,1-2H3,(H,24,26)(H,27,28)/b12-11+
|
| DBBrand | cinalukast [usan:inn]
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |