Preferred Name | sulfisoxazole | |
Synonyms |
4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide Sulphofurazole N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide 3,4-Dimethyl-5-sulfonamidoisoxazole 3,4-Dimethyl-5-sulphanilamidoisoxazole Sulphafurazole Sulfasoxazole 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole 3,4-Dimethyl-5-sulphonamidoisoxazole Sulfisoxazol Sulfadimethylisoxazole 5-Sulphanilamido-3,4-dimethyl-isoxazole Sulphaisoxazole Sulfisonazole 5-Sulfanilamido-3,4-dimethylisoxazole Sulfaisoxazole 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide Sulphafurazol C11H13N3O3S 3,4-Dimethyl-5-sulfanilamidoisoxazole Sulphisoxazol N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide Sulfofurazole sulfafurazolum sulfafurazole 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole Sulfisoxasole Sulfafurazol Sulphadimethylisoxazole 3,4-Dimethylisoxazole-5-sulphanilamide 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole 4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide 3,4-Dimethylisoxazole-5-sulfanilamide N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide |
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ID |
http://purl.obolibrary.org/obo/CHEBI_102484 |
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AHFScode |
08:12.20 |
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altId |
CHEBI:9343 |
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ATCCode |
J01EB05 S01AB02 |
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binds | ||
CASRN |
127-69-5 |
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DBBrand |
tl-azole azosulfizin soxamide gantrisin sulfalar soxitabs bactesulf dorsulfan gantrisine sulsoxin azo gantrisin sulfasan uritrisin gantrosan soxomide sulfizole sulfapolar unisulf neazolin v-sul soxo urogan entusul sulfazin koro-sulf accuzole sulphafuraz renosulfan sulfizol j-sul urisoxin sulbio sulfoxol g-sox ganda soxazole gantrisona chemouag suloxsol saxosozine sosol alphazole barazae vagilia amidoxal sulfisin roxosul tablets thiasin sk-soxazole sulfagan entusil sulfasol neoxazol dorsulfan warthausen soxisol novazolo isoxamin sulfagen astrazolo novosaxazole resoxol stansin pancid roxosul sodizole norilgan-s sulfizin roxoxol cosoxazole |
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DBname |
sulfisoxazole |
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DBSynonym |
sulfadimethylisoxazole sulphafurazole sulfisoxazole dialamine sulfasoxazole sulphofurazole sulfisonazole sulphafurazolum sulfisoxazole diolamine sulphafurazol sulfafurazol sulphaisoxazole sulfafurazole sulfofurazole sulfisoxazol sulphisoxazol sulfaisoxazole sulfisoxasole |
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Definition |
A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. |
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has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000283 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0000526 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0001145 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001030 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0001749 |
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has pharmacological target | ||
has role | ||
InChI |
InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3 |
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InChIKey |
InChIKey=NHUHCSRWZMLRLA-UHFFFAOYSA-N |
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inhibits | ||
is metabolised by | ||
is substrate of | ||
label |
sulfisoxazole |
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may interact with |
http://purl.obolibrary.org/obo/CHEBI_10100 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_3650 http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/dinto_DB00214 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00440 |
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prefixIRI |
obo2:CHEBI_102484 |
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prefLabel |
sulfisoxazole |
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SMILES |
CC1=NOC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1C Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C |
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Synonym |
4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide Sulphofurazole N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide 3,4-Dimethyl-5-sulfonamidoisoxazole 3,4-Dimethyl-5-sulphanilamidoisoxazole Sulphafurazole Sulfasoxazole 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole 3,4-Dimethyl-5-sulphonamidoisoxazole Sulfisoxazol Sulfadimethylisoxazole 5-Sulphanilamido-3,4-dimethyl-isoxazole Sulphaisoxazole Sulfisonazole 5-Sulfanilamido-3,4-dimethylisoxazole Sulfaisoxazole 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide Sulphafurazol C11H13N3O3S 3,4-Dimethyl-5-sulfanilamidoisoxazole Sulphisoxazol N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide Sulfofurazole sulfafurazolum sulfafurazole 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole Sulfisoxasole Sulfafurazol Sulphadimethylisoxazole 3,4-Dimethylisoxazole-5-sulphanilamide 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole 4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide 3,4-Dimethylisoxazole-5-sulfanilamide N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide |
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xref |
PubChem Substance:46505342 Wikipedia:Sulfisoxazole CASRN:127-69-5 CiteXplore:4960234 NIST Chemistry WebBook:127-69-5 PharmGKB:PA164748964 Wikipedia:http://en.wikipedia.org/wiki/Sulfisoxazole Drugs.com:http://www.drugs.com/mtm/sulfisoxazole-ophthalmic.html Beilstein:263871 BindingDB:50034452 National Drug Code Directory:0004-1003-28 ChEBI:102484 DrugBank:DB00263 KEGG COMPOUND:C07318 KEGG DRUG:D00450 ChemSpider:5151 Gmelin:864477 Drugs Product Database (DPD):363774 Patent:US2430094 CiteXplore:7356572 PubChem Compound:5344 CiteXplore:1861917 |
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subClassOf |