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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_10112
http://purl.obolibrary.org/obo/CHEBI_10112
|
|---|---|
| Preferred Name | zileuton |
| Synonyms |
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Leutrol
Zileuton
Zyflo
C11H12N2O2S
1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
zileutonum
zileuton
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | zileuton
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|---|---|
| label | zileuton
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| DBSynonym | zileutonum [inn-latin]
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| Definition | A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=MWLSOWXNZPKENC-UHFFFAOYSA-N
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| is metabolised by | |
| Synonym |
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Leutrol
Zileuton
Zyflo
C11H12N2O2S
1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
zileutonum
zileuton
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|
| xref |
ChEMBL:109217
KEGG DRUG:D00414
CASRN:111406-87-2
DrugBank:DB00744
Reaxys:4869674
ChEBI:10112
CiteXplore:19645854
Wikipedia:http://en.wikipedia.org/wiki/Zileuton
PubChem Compound:60490
CiteXplore:19309543
RxList:http://www.rxlist.com/cgi/generic/zileuton.htm
PubChem Substance:46506394
Drugs.com:http://www.drugs.com/cdi/zileuton.html
CiteXplore:20436887
National Drug Code Directory:68734-700-10
PharmGKB:PA451955
Wikipedia:Zileuton
CiteXplore:20204486
ChemSpider:54531
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| CASRN | 111406-87-2
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| prefixIRI | obo2:CHEBI_10112
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| SMILES |
CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1
CC(N(O)C(N)=O)c1cc2ccccc2s1
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| may interact with |
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| DBname | zileuton
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| InChI | InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
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| DBBrand |
zyflo cr
zyflo
leutrol
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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