The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_10110 http://purl.obolibrary.org/obo/CHEBI_10110
Preferred Name	zidovudine
Synonyms	AZT zidovudine 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Zidovudinum Azidothymidine C10H13N5O4 3'-azido-3'-deoxythymidine Zidovudin
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	zidovudine
label	zidovudine
DBSynonym	zdv compound s azidothymidine
ATCCode	J05AF01
Definition	A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
altId	CHEBI:619601
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001378 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000671 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000286 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000613 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000752 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0001418 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1703
inhibits	http://purl.obolibrary.org/obo/dinto_1703 http://purl.obolibrary.org/obo/dinto_2378
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_53756 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_36044
InChIKey	InChIKey=HBOMLICNUCNMMY-XLPZGREQSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_3034 See more See less
AHFScode	08:18.08.20
Synonym	AZT zidovudine 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Zidovudinum Azidothymidine C10H13N5O4 3'-azido-3'-deoxythymidine Zidovudin See more See less
xref	DrugBank:DB00495 ChemSpider:32555 KEGG COMPOUND:C07210 BindingDB:50002692 Drugs.com:http://www.drugs.com/cdi/zidovudine.html PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ret1375.shtml KEGG DRUG:D00413 PharmGKB:PA451954 National Drug Code Directory:0173-0107-93 RxList:http://www.rxlist.com/cgi/generic3/zidovud.htm PubChem Compound:35370 Wikipedia:Zidovudine Drugs Product Database (DPD):1946323 ChEMBL:127307 CASRN:30516-87-1 Wikipedia:http://en.wikipedia.org/wiki/Zidovudine Patent:US4724232 PubChem Substance:46508240 ChEBI:10110 DrugBank:30516-87-1 Beilstein:763034 ChEMBL:19112024 See more See less
CASRN	30516-87-1
prefixIRI	obo2:CHEBI_10110
is transported by	http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1992 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_0300
related with	http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_1692 http://purl.obolibrary.org/obo/dinto_1690 http://purl.obolibrary.org/obo/dinto_0217 See more See less
SMILES	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O
may interact with	http://purl.obolibrary.org/obo/dinto_DB00649 http://purl.obolibrary.org/obo/CHEBI_63580 http://purl.obolibrary.org/obo/dinto_DB00997 http://purl.obolibrary.org/obo/CHEBI_575568 http://purl.obolibrary.org/obo/CHEBI_45304 http://purl.obolibrary.org/obo/CHEBI_63635 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/CHEBI_6807 http://purl.obolibrary.org/obo/CHEBI_45367 http://purl.obolibrary.org/obo/CHEBI_465284 http://purl.obolibrary.org/obo/CHEBI_63628 http://purl.obolibrary.org/obo/dinto_DB00068 http://purl.obolibrary.org/obo/CHEBI_8426 http://purl.obolibrary.org/obo/CHEBI_28077 See more See less
DBname	zidovudine
InChI	InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
DBBrand	apo-zidovudine compound s aztec novo-azt retrovir zidovudine ep iii See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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