The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_10093 http://purl.obolibrary.org/obo/CHEBI_10093
Preferred Name	yohimbine
Synonyms	methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate Johimbin (+)-yohimbine quebrachine 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester aphrodine Yohimbine methyl 17alpha-hydroxyyohimban-16alpha-carboxylate yohimbic acid methyl ester Yohimbin (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester Quebrachin corynine C21H26N2O3 See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	yohimbine
label	yohimbine
DBSynonym	yohimbin
ATCCode	G04BE04
Definition	An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_1135
inhibits	http://purl.obolibrary.org/obo/dinto_2993
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_48279 http://purl.obolibrary.org/obo/CHEBI_37890
InChIKey	InChIKey=BLGXFZZNTVWLAY-SCYLSFHTSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901
blocks	http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_4010 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_2858 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_3332 http://purl.obolibrary.org/obo/dinto_1135 See more See less
AHFScode	92:00.00
Synonym	methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate Johimbin (+)-yohimbine quebrachine 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester aphrodine Yohimbine methyl 17alpha-hydroxyyohimban-16alpha-carboxylate yohimbic acid methyl ester Yohimbin (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester Quebrachin corynine C21H26N2O3 See more See less
xref	Beilstein:4720812 PubChem Compound:8969 ChEMBL:115191 Drugs.com:http://www.drugs.com/cdi/yohimbine.html Drugs Product Database (DPD):795283 CASRN:146-48-5 ChemSpider:8622 Wikipedia:http://en.wikipedia.org/wiki/Yohimbine PharmGKB:PA451946 PubChem Substance:46504602 Beilstein:97276 KEGG DRUG:D08685 KEGG COMPOUND:C09256 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/yoc1492.shtml NIST Chemistry WebBook:146-48-5 ChEBI:10093 RxList:http://www.rxlist.com/cgi/generic/yohimbine.htm DrugBank:DB01392 See more See less
CASRN	146-48-5
prefixIRI	obo2:CHEBI_10093
related with	http://purl.obolibrary.org/obo/dinto_1166
SMILES	[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2 [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCc3c1[nH]c1ccccc31)C2
may interact with	http://purl.obolibrary.org/obo/CHEBI_127342 http://purl.obolibrary.org/obo/CHEBI_71253
DBname	yohimbine
InChI	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1
DBBrand	yocon baron-x dayto himbin yovital actibine yoman thybine aphrodyne yohimex yohimar See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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