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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_100246
http://purl.obolibrary.org/obo/CHEBI_100246
|
|---|---|
| Preferred Name | norfloxacin |
| Synonyms |
NFLX
norfloxacine
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
norfloxacino
1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
norfloxacinum
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
C16H18FN3O3
norfloxacin
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | norfloxacin
|
|---|---|
| label | norfloxacin
|
| ATCCode |
J01MA06
S01AE02
|
| Definition | A synthetic fluoroquinolone with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
|
| altId | CHEBI:7629
|
| has effect |
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| has pharmacological target | |
| inhibits |
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|
| type | |
| has role | |
| InChIKey | InChIKey=OGJPXUAPXNRGGI-UHFFFAOYSA-N
|
| AHFScode | 08:12.18
|
| Synonym |
NFLX
norfloxacine
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
norfloxacino
1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
norfloxacinum
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
C16H18FN3O3
norfloxacin
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|
| xref |
BindingDB:50045000
CiteXplore:3908074
Wikipedia:http://en.wikipedia.org/wiki/Norfloxacin
CiteXplore:6211142
Gmelin:1576626
Patent:DE2840910
Patent:US4146719
CASRN:70458-96-7
CiteXplore:3317294
ChEBI:100246
CiteXplore:6461606
KEGG COMPOUND:C06687
Patent:BE863429
Patent:US4292317
Drugs.com:http://www.drugs.com/mtm/norfloxacin-ophthalmic.html
ChemSpider:4380
RxList:http://www.rxlist.com/cgi/generic3/norfloxacin.htm
PharmGKB:PA450654
CiteXplore:6234465
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/nor1302.shtml
PubChem Compound:4539
KEGG DRUG:D00210
Beilstein:567897
DrugBank:DB01059
CiteXplore:6454381
Wikipedia:Norfloxacin
PubChem Substance:46508634
CiteXplore:6224685
National Drug Code Directory:0006-0705-68
Drugs Product Database (DPD):2246596
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| CASRN | 70458-96-7
|
| prefixIRI | obo2:CHEBI_100246
|
| SMILES |
CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1
|
| may interact with |
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| DBname | norfloxacin
|
| InChI | InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
|
| DBBrand |
chibroxin
noroxin
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |