Preferred Name

MolecularInteraction

Definitions

Definition: An interaction in which participants bind physically to each other,directly or indirectly through intermediary molecules. Rationale: There is a large body of interaction data, mostly produced by high throughput systems, that does not satisfy the level of detail required to model them with ComplexAssembly class. Specifically, what is lacking is the stoichiometric information and completeness ( closed-world) of participants required to model them as chemical processes. Nevertheless interaction data is extremely useful and can be captured in BioPAX using this class. Usage: This class should be used by default for representing molecular interactions, such as those defined by PSI-MI level 2.5. The participants in a molecular interaction should be listed in the PARTICIPANTS slot. Note that this is one of the few cases in which the PARTICPANT slot should be directly populated with instances (see comments on the PARTICPANTS property in the interaction class description). If all participants are known with exact stoichiometry, ComplexAssembly class should be used instead. Example: Two proteins observed to interact in a yeast-two-hybrid experiment where there is not enough experimental evidence to suggest that the proteins are forming a complex by themselves without any indirect involvement of other proteins. This is the case for most large-scale yeast two-hybrid screens. Definition: An interaction in which participants bind physically to each other, directly or indirectly through intermediary molecules. Rationale: There is a large body of interaction data, mostly produced by high throughput systems, that does not satisfy the level of detail required to model them with ComplexAssembly class. Specifically, what is lacking is the stoichiometric information and completeness (closed-world) of participants required to model them as chemical processes. Nevertheless interaction data is extremely useful and can be captured in BioPAX using this class. Usage: This class should be used by default for representing molecular interactions such as those defined by PSI-MI level 2.5. The participants in a molecular interaction should be listed in the PARTICIPANT slot. Note that this is one of the few cases in which the PARTICPANT slot should be directly populated with instances (see comments on the PARTICPANTS property in the interaction class description). If all participants are known with exact stoichiometry, ComplexAssembly class should be used instead. Example: Two proteins observed to interact in a yeast-two-hybrid experiment where there is not enough experimental evidence to suggest that the proteins are forming a complex by themselves without any indirect involvement of other proteins. This is the case for most large-scale yeast two-hybrid screens.

ID

http://www.biopax.org/release/biopax-level3.owl#MolecularInteraction

comment

Definition: An interaction in which participants bind physically to each other,directly or indirectly through intermediary molecules. Rationale: There is a large body of interaction data, mostly produced by high throughput systems, that does not satisfy the level of detail required to model them with ComplexAssembly class. Specifically, what is lacking is the stoichiometric information and completeness ( closed-world) of participants required to model them as chemical processes. Nevertheless interaction data is extremely useful and can be captured in BioPAX using this class. Usage: This class should be used by default for representing molecular interactions, such as those defined by PSI-MI level 2.5. The participants in a molecular interaction should be listed in the PARTICIPANTS slot. Note that this is one of the few cases in which the PARTICPANT slot should be directly populated with instances (see comments on the PARTICPANTS property in the interaction class description). If all participants are known with exact stoichiometry, ComplexAssembly class should be used instead. Example: Two proteins observed to interact in a yeast-two-hybrid experiment where there is not enough experimental evidence to suggest that the proteins are forming a complex by themselves without any indirect involvement of other proteins. This is the case for most large-scale yeast two-hybrid screens.

Definition: An interaction in which participants bind physically to each other, directly or indirectly through intermediary molecules. Rationale: There is a large body of interaction data, mostly produced by high throughput systems, that does not satisfy the level of detail required to model them with ComplexAssembly class. Specifically, what is lacking is the stoichiometric information and completeness (closed-world) of participants required to model them as chemical processes. Nevertheless interaction data is extremely useful and can be captured in BioPAX using this class. Usage: This class should be used by default for representing molecular interactions such as those defined by PSI-MI level 2.5. The participants in a molecular interaction should be listed in the PARTICIPANT slot. Note that this is one of the few cases in which the PARTICPANT slot should be directly populated with instances (see comments on the PARTICPANTS property in the interaction class description). If all participants are known with exact stoichiometry, ComplexAssembly class should be used instead. Example: Two proteins observed to interact in a yeast-two-hybrid experiment where there is not enough experimental evidence to suggest that the proteins are forming a complex by themselves without any indirect involvement of other proteins. This is the case for most large-scale yeast two-hybrid screens.

prefixIRI

MolecularInteraction

bp:MolecularInteraction

prefLabel

MolecularInteraction

subClassOf

http://www.biopax.org/release/biopax-level3.owl#Interaction

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http://purl.obolibrary.org/obo/IEV_0001886 PTS LOOM
http://purl.obolibrary.org/obo/MI_0190 RETO LOOM
http://purl.obolibrary.org/obo/MI_0190 GEXO LOOM
http://purl.obolibrary.org/obo/MI_0190 REXO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://purl.bioontology.org/ontology/GSSO/000723 GSSO LOOM
http://bioontology.org/ontologies/BiomedicalResourceOntology.owl#Molecular_Interaction BRO_ACRONYM LOOM
http://bioontology.org/ontologies/BiomedicalResourceOntology.owl#Molecular_Interaction BRO LOOM
http://bioontology.org/ontologies/BiomedicalResourceOntology.owl#Molecular_Interaction DINTO LOOM
http://www.bootstrep.eu/ontology/GRO#MolecularInteraction GRO LOOM
http://purl.obolibrary.org/obo/MI_0000 MI LOOM
http://purl.obolibrary.org/obo/MI_0000 MI LOOM
http://purl.obolibrary.org/obo/MI_0000 MI LOOM
http://purl.obolibrary.org/obo/MI_0000 MI LOOM
http://purl.obolibrary.org/obo/MI_0000 MI LOOM
http://purl.bioontology.org/net/brunel/panda#MolecularInteraction PANDA LOOM
http://www.cvrgrid.org/files/ECGOntologyv1.owl#ECG_000000437 ECG LOOM
http://purl.org/obo/owl/SBO#SBO_0000344 HUPSON LOOM
http://www.semanticweb.org/DMO#molecular_interaction ADMO LOOM
http://www.biopax.org/release/biopax-level3.owl#MolecularInteraction BP LOOM
http://www.biopax.org/release/biopax-level3.owl#MolecularInteraction BP SAME_URI
http://www.biopax.org/release/biopax-level3.owl#MolecularInteraction MIM LOOM
http://www.biopax.org/release/biopax-level3.owl#MolecularInteraction MIM SAME_URI