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Drug Interaction Knowledge Base Ontology
Last uploaded:
May 19, 2015
Acronym | DIKB |
Visibility | Public |
Description | An evidence taxonomy for pharmacologic studies that, when combined with a set of inclusion criteria, enable drug experts to specify what their confidence in a drug mechanism assertion would be if it were supported by a specific set of evidence. Boyce R, Collins C, Horn J, Kalet I. Computing with evidence Part I: A drug-mechanism evidence taxonomy oriented toward confidence assignment. J Biomed Inform. 2009 Dec;42(6):979-89. Epub 2009 May 10. PubMed PMID: 19435613; PubMed Central PMCID: PMC2783801. |
Status | Beta |
Format | OWL |
Contact | Richard D Boyce, rdb20@pitt.edu |
Categories | Vocabularies |
Version | Released | Uploaded | Downloads |
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Version 1.6 (Parsed, Indexed, Metrics, Annotator) | 05/18/2015 | 05/19/2015 | OWL | CSV | RDF/XML | Diff |
Version 1.6 (Archived) | 05/18/2015 | 05/18/2015 | OWL | Diff |
The Dug Interaction Knowledge Base ontology. This version is essentially the original version from 2007 with a change to the base IRI to use a PURL (Archived) | 10/14/2011 | 02/09/2013 | OWL | Diff |
1.4 (Archived) | 10/14/2011 | 06/18/2012 | OWL | Diff |
0.2 (Archived) | 10/14/2011 | 10/14/2011 | OWL |
more... |
No views of DIKB available
Classes | 161 |
Individuals | 9 |
Properties | 138 |
Maximum depth | 4 |
Maximum number of children | 25 |
Average number of children | 2 |
Classes with a single child | 26 |
Classes with more than 25 children | 1 |
Classes with no definition | 14 |
Jump to:
Id | http://www.biopax.org/release/biopax-level3.owl#Conversion
http://www.biopax.org/release/biopax-level3.owl#Conversion
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Preferred Name | Conversion |
Definitions |
Definition: An interaction in which molecules of one or more physicalEntity pools are physically transformed and become a member of one or more other physicalEntity pools.
Comments: Conversions in BioPAX are stoichiometric and closed world, i.e. i is assumed that all of the participants are listed. Both properties are due to the law of mass conservation.
Usage: Subclasses of conversion represent different types of transformation reflected by different physicalEntity properties. BiochemicalReaction will change the ModificationFeatures on the PhysicalEntity , Transport will change the CellularLocation and ComplexAssembly will change the BindingFeature. Generic Conversion class should only be used when the modification does not fit into one of these classes.
Example: Opening of a voltage gated channel.
Definition: An interaction in which molecules of one or more PhysicalEntity pools are physically transformed and become a member of one or more other PhysicalEntity pools.
Rationale: Conversion is Comments: Conversions in BioPAX are stoichiometric and closed world, i.e. it is assumed that all of the participants are listed. Both properties are due to the law of mass conservation.
Usage: Subclasses of conversion represent different types of transformation reflected by the properties of different physicalEntity. BiochemicalReactions will change the ModificationFeatures on a PhysicalEntity, Transport will change the Cellular Location and ComplexAssembly will change BindingFeatures. Generic Conversion class should only be used when the modification does not fit into a any of these classes.
Example: Opening of a voltage gated channel.
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
comment | Definition: An interaction in which molecules of one or more physicalEntity pools are physically transformed and become a member of one or more other physicalEntity pools.
Comments: Conversions in BioPAX are stoichiometric and closed world, i.e. i is assumed that all of the participants are listed. Both properties are due to the law of mass conservation.
Usage: Subclasses of conversion represent different types of transformation reflected by different physicalEntity properties. BiochemicalReaction will change the ModificationFeatures on the PhysicalEntity , Transport will change the CellularLocation and ComplexAssembly will change the BindingFeature. Generic Conversion class should only be used when the modification does not fit into one of these classes.
Example: Opening of a voltage gated channel.
Definition: An interaction in which molecules of one or more PhysicalEntity pools are physically transformed and become a member of one or more other PhysicalEntity pools.
Rationale: Conversion is Comments: Conversions in BioPAX are stoichiometric and closed world, i.e. it is assumed that all of the participants are listed. Both properties are due to the law of mass conservation.
Usage: Subclasses of conversion represent different types of transformation reflected by the properties of different physicalEntity. BiochemicalReactions will change the ModificationFeatures on a PhysicalEntity, Transport will change the Cellular Location and ComplexAssembly will change BindingFeatures. Generic Conversion class should only be used when the modification does not fit into a any of these classes.
Example: Opening of a voltage gated channel.
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prefLabel | Conversion
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prefixIRI |
Conversion
bp:Conversion
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subClassOf | |
type | |
disjointWith |
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Example 1 (start typing the class name to get its full URI)
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <iframe frameborder="0" src="/widgets/visualization?ontology=DIKB&class=http%3A%2F%2Fpurl.org%2Fnet%2Fdrug-interaction-knowledge-base%2FDIKB_evidence_ontology.owl%23in_vitro_Protein_Source&apikey=YOUR_API_KEY"></iframe> For more help visit NCBO Widget Wiki |
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <link rel="stylesheet" type="text/css" href="/widgets/jquery.ncbo.tree.css"> <script src="/widgets/jquery.ncbo.tree-2.0.2.js"></script> <div id="widget_tree"></div> var widget_tree = $("#widget_tree").NCBOTree({ apikey: "YOUR_API_KEY", ontology: "DIKB" }); You can also view a detailed demonstration For more help visit NCBO Widget Wiki |