Cigarette Smoke Exposure Ontology

Last uploaded: July 10, 2014

Id	http://scai.fraunhofer.de/CSEO#CSEO_00000864 http://scai.fraunhofer.de/CSEO#CSEO_00000864
Preferred Name	Free Radical
Type	http://www.w3.org/2002/07/owl#Class

label	Free Radical
prefLabel	Free Radical
Synonym	Radical
isDefinedBy	Molecules or atoms with at least one unpaired or 'free' electron in the outermost electron shell. Chemically unstable, free radicals stabilize themselves by appropriating an electron from a nearby molecule, thereby damaging that molecule by altering the electron number in its outermost electron shell. By-products of both normal cell processes and environmental toxin exposure, oxygen free-radicals in high concentrations may damage DNA, proteins, and lipids, thereby increasing the risk for various diseases including cancer. (NCI04)
Reference	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Free_Radicals
prefixIRI	CSEO_00000864
subClassOf	http://scai.fraunhofer.de/CSEO#CSEO_00000863
type	http://www.w3.org/2002/07/owl#Class
source	http://purl.bioontology.org/ontology/RCD/Xa4gL http://purl.bioontology.org/ontology/CSP/1010-1403 http://purl.bioontology.org/ontology/SNOMEDCT/39265005 http://purl.obolibrary.org/obo/chebi.owl#CHEBI_26519 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Free_Radicals

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