Preferred Name | Immunohistochemistry Staining Method | |
Synonyms |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Immunohistochemistry_Staining_Method |
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DEFINITION |
Immunohistochemical staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen. |
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FULL_SYN |
Immunohistochemistry Cell/Tissue, Immunohistochemistry IHC |
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isDefinedBy |
Immunohistochemical staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen. |
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label |
Immunohistochemistry Staining Method |
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prefixIRI |
Thesaurus:Immunohistochemistry_Staining_Method |
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prefLabel |
Immunohistochemistry Staining Method |
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Synonym |
Immunohistochemistry Cell/Tissue, Immunohistochemistry IHC |
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subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Special_Histology_Staining_Method |
Delete | Mapping To | Ontology | Source |
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http://purl.bioontology.org/ontology/PDQ/CDR0000042769 | PDQ | LOOM | |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23020 | NCIT | LOOM |