loading...| Preferred Name |
MHC class I antigen |
|
| Synonyms |
H2K antigen HLA G antigen HLA A antigen H2D antigen HLA B antigen HLA C antigen |
|
| Definitions |
large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders. |
|
| ID |
http://purl.bioontology.org/ontology/CSP/2935-6332 |
|
| altLabel |
H2K antigen HLA G antigen HLA A antigen H2D antigen HLA B antigen HLA C antigen |
|
| cui |
C0019737 C0019728 C0082920 C0019629 C0599838 C0019751 C0599837 |
|
| definition |
large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders. |
|
| DID |
2935-6332 |
|
| Inverse of RB | ||
| Inverse of RO | ||
| notation |
2935-6332 |
|
| prefLabel |
MHC class I antigen |
|
| tui |
T116 T129 T121 |
|
| subClassOf |