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Last uploaded:
August 28, 2024
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| Preferred Name | MHC class I antigen | |
| Synonyms |
H2K antigen HLA G antigen HLA A antigen H2D antigen HLA B antigen HLA C antigen |
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| Definitions |
large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders. |
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| ID |
http://purl.bioontology.org/ontology/CSP/2935-6332 |
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| altLabel |
H2K antigen HLA G antigen HLA A antigen H2D antigen HLA B antigen HLA C antigen
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| cui |
C0019737 C0019728 C0082920 C0019629 C0599838 C0019751 C0599837
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|
| definition |
large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders.
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| DID |
2935-6332
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| Inverse of RB | ||
| Inverse of RO | ||
| notation |
2935-6332
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|
| prefLabel |
MHC class I antigen
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|
| tui |
T116 T129 T121
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| subClassOf |
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