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Last uploaded:
September 25, 2013
| Id | http://purl.bioontology.org/ontology/CSP/2935-6332
http://purl.bioontology.org/ontology/CSP/2935-6332
|
|---|---|
| Preferred Name | MHC class I antigen |
| Definitions |
large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders.
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| Synonyms |
H2K antigen
HLA G antigen
HLA A antigen
H2D antigen
HLA B antigen
HLA C antigen
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders. |
|---|---|
| altLabel |
H2K antigen
HLA G antigen
HLA A antigen
H2D antigen
HLA B antigen
HLA C antigen
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|
| prefLabel | MHC class I antigen
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| Inverse of RO | |
| type | |
| tui |
T116
T129
T121
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| notation | 2935-6332
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| Semantic type UMLS property | |
| DID | 2935-6332
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| cui |
C0019737
C0019728
C0082920
C0019629
C0599838
C0019751
C0599837
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| Inverse of RB | |
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |