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Last uploaded:
August 28, 2024
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| Preferred Name | cardiac glycoside | |
| Synonyms |
digitoxin |
|
| Definitions |
group of substances obtained from species of Digitalis, Strophanthus, and other plants that contain specific steroid glycosides or their semisynthetic derivatives and used in congestive heart failure; they increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses; their mechanism of action usually involves inhibition of the Na(+)-K(+)-exchanging ATPase and they are often used in cell biological studies for that purpose. |
|
| ID |
http://purl.bioontology.org/ontology/CSP/0567-0162 |
|
| altLabel |
digitoxin
|
|
| cui |
C0007158 C0012258
|
|
| definition |
group of substances obtained from species of Digitalis, Strophanthus, and other plants that contain specific steroid glycosides or their semisynthetic derivatives and used in congestive heart failure; they increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses; their mechanism of action usually involves inhibition of the Na(+)-K(+)-exchanging ATPase and they are often used in cell biological studies for that purpose.
|
|
| DID |
0567-0162
|
|
| Inverse of RB |
http://purl.bioontology.org/ontology/CSP/0551-6495 |
|
| Inverse of RN | ||
| notation |
0567-0162
|
|
| prefLabel |
cardiac glycoside
|
|
| tui |
T109 T121
|
|
| subClassOf |
http://purl.bioontology.org/ontology/CSP/0551-6495 |
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