COVID-19 Ontology

Last uploaded: February 25, 2021
Preferred Name

CD4-Positive T-Lymphocytes

Synonyms
ID

http://purl.obolibrary.org/obo/OMIT_0016234

fromArticle

true

fromBEL

true

imported from

http://purl.obolibrary.org/obo/omit.owl

label

CD4-Positive T-Lymphocytes

oboInOwl:hasDefinition

A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.

preferred label

CD4-Positive T-Lymphocytes

prefixIRI

OMIT:0016234

prefLabel

CD4-Positive T-Lymphocytes

see also

https://www.medrxiv.org/content/10.1101/2020.02.18.20024364v1

subClassOf

http://purl.obolibrary.org/obo/CL_0000084

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