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COVID-19 Ontology
Last uploaded:
February 25, 2021
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| Id | http://purl.obolibrary.org/obo/NCIT_C16389
http://purl.obolibrary.org/obo/NCIT_C16389
|
|---|---|
| Preferred Name | Cathepsin |
| Definitions |
Lysosomal proteinases or endopeptidases that function optimally at an acidic pH to catalyze the hydrolysis of peptidic bonds. Elevated cathepsin enzyme activity in either serum or extracellular matrix is often indicative of pathological conditions such as Alzheimer's disease, several types of cancer, arthritis, and osteoporosis.
|
| Synonyms |
Cathepsin
Cathepsins
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Lysosomal proteinases or endopeptidases that function optimally at an acidic pH to catalyze the hydrolysis of peptidic bonds. Elevated cathepsin enzyme activity in either serum or extracellular matrix is often indicative of pathological conditions such as Alzheimer's disease, several types of cancer, arthritis, and osteoporosis. |
|---|---|
| preferred label |
Cathepsin
|
| label |
Cathepsin
|
| prefLabel |
Cathepsin
|
| oboInOwl:hasDbXRef | |
| Legacy_Concept_Name |
Cathepsin
|
| in_subset | |
| Preferred_Name |
Cathepsin
|
| fromBEL |
true
|
| Display_Name |
Cathepsin
|
| fromPubMed |
true
|
| UMLS_CUI |
C0007428
|
| prefixIRI |
NCIT:C16389
|
| textual definition |
Lysosomal proteinases or endopeptidases that function optimally at an acidic pH to catalyze the hydrolysis of peptidic bonds. Elevated cathepsin enzyme activity in either serum or extracellular matrix is often indicative of pathological conditions such as Alzheimer's disease, several types of cancer, arthritis, and osteoporosis.
|
| Contributing_Source |
CTRP
|
| subClassOf | |
| imported from | |
| code |
C16389
|
| type | |
| alternative_term |
Cathepsin
Cathepsins
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
|
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