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COVID-19 Ontology
Last uploaded:
February 25, 2021
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| Preferred Name | Enoxaparin | |
| Synonyms |
ENOXAPARIN Enoxaparin enoxaparin |
|
| Definitions |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1452 |
|
| ALT_DEFINITION |
A drug used to prevent blood clots. It belongs to the family of drugs called anticoagulants.
|
|
| alternative_term |
ENOXAPARIN Enoxaparin enoxaparin
|
|
| CAS_Registry |
9005-49-6
|
|
| CHEBI_ID |
CHEBI:28304
|
|
| Chemical_Formula |
(C14H18NO11)n.C14H18NO11.C12H17NO12S.(C12H16NO13S)n.C12H15NO13S.Na.H.5HO3S
|
|
| code |
C1452
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04)
|
|
| Display_Name |
Enoxaparin
|
|
| FDA_UNII_Code |
E47C0NF7LV
|
|
| imported from | ||
| in_subset |
http://purl.oboInOwllibrary.org/oboInOwl/NCIT_C116977 |
|
| label |
Enoxaparin
|
|
| Legacy_Concept_Name |
Enoxaparin
|
|
| NSC_Code |
728167
|
|
| PDQ_Closed_Trial_Search_ID |
37880
|
|
| PDQ_Open_Trial_Search_ID |
37880
|
|
| preferred label |
Enoxaparin
|
|
| Preferred_Name |
Enoxaparin
|
|
| prefixIRI |
NCIT:C1452
|
|
| prefLabel |
Enoxaparin
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| textual definition |
A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04)
|
|
| UMLS_CUI |
C0206460
|
|
| subClassOf |
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