COVID-19 Ontology

Last uploaded: February 25, 2021
Preferred Name

Recombinant Granulocyte Colony-Stimulating Factor
Synonyms

Recombinant Colony-Stimulating Factor 3

Recombinant Granulocyte Colony-Stimulating Factor

rhG-CSF

Definitions

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)

ID

http://purl.obolibrary.org/obo/NCIT_C1287

Accepted_Therapeutic_Use_For

Neutropenia

alternative_term

Recombinant Colony-Stimulating Factor 3

Recombinant Granulocyte Colony-Stimulating Factor

rhG-CSF

CAS_Registry

143011-72-7

code

C1287

definition

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)

fromArticle

true

imported from

http://purl.obolibrary.org/obo/ncit.owl

label

Recombinant Granulocyte Colony-Stimulating Factor

Legacy_Concept_Name

Recombinant_Granulocyte_Colony_Stimulating_Factor

NSC_Code

614371

614629

PDQ_Closed_Trial_Search_ID

618712

PDQ_Open_Trial_Search_ID

618712

preferred label

Recombinant Granulocyte Colony-Stimulating Factor

Preferred_Name

Recombinant Granulocyte Colony-Stimulating Factor

prefixIRI

NCIT:C1287

prefLabel

Recombinant Granulocyte Colony-Stimulating Factor

see also

https://www.cebm.net/covid-19/registered-trials-and-analysis/

Semantic_Type

Amino Acid, Peptide, or Protein

Immunologic Factor

textual definition

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)

UMLS_CUI

C0376562

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888

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