COVID-19 Ontology

Last uploaded: February 25, 2021
Preferred Name

nitazoxanide
Synonyms
ID

http://purl.obolibrary.org/obo/DRON_00015413

fromPubMed

true

has_RxCUI

31819

imported from

http://purl.obolibrary.org/obo/dron.owl

label

nitazoxanide

oboInOwl:hasDbXRef

https://www.ncbi.nlm.nih.gov/pubmed/32293834

oboInOwl:hasDefinition

A synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. PFOR enzyme reduces nitazoxanide, thereby impairing the energy metabolism.

preferred label

nitazoxanide

prefixIRI

DRON:00015413

prefLabel

nitazoxanide

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888

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http://purl.obolibrary.org/obo/DRON_00015413 DRON SAME_URI
http://purl.obolibrary.org/obo/DRON_00015413 PDRO SAME_URI
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http://purl.obolibrary.org/obo/DRON_00015413 CIDO SAME_URI
http://purl.obolibrary.org/obo/DRON_00015413 DRON SAME_URI
http://purl.obolibrary.org/obo/DRON_00015413 DRON LOOM
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http://purl.obolibrary.org/obo/DRON_00015413 DDSS LOOM
http://purl.obolibrary.org/obo/DRON_00015413 CIDO LOOM
http://purl.obolibrary.org/obo/DRON_00015413 DRON LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000769610 PDQ LOOM
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http://www.phoc.org.cn/pmo/class/PMO_00026691 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/006303 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/407148001 SNOMEDCT LOOM