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COVID-19 Ontology
Last uploaded:
February 25, 2021
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| Id | http://purl.obolibrary.org/obo/CHEBI_5801
http://purl.obolibrary.org/obo/CHEBI_5801
|
|---|---|
| Preferred Name | hydroxychloroquine |
| Definitions |
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
|
| Synonyms |
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
oxichloroquine
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
hydroxychloroquine
(+-)-hydroxychloroquine
Polirreumin
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
hidroxicloroquina
7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
hydroxychloroquinum
oxichlorochine
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
NSC4375
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. |
|---|---|
| preferred label |
hydroxychloroquine
|
| label |
hydroxychloroquine
|
| prefLabel |
hydroxychloroquine
|
| oboInOwl:hasDbXRef | |
| database_cross_reference |
DrugBank:DB01611
KEGG:C07043
HMDB:HMDB0015549
KEGG:D08050
PMID:23485647
PMID:23481418
PMID:23218706
CAS:118-42-3
Drug_Central:1395
Wikipedia:Hydroxychloroquine
Reaxys:253894
PMID:23216212
LINCS:LSM-5193
PMID:23902281
Patent:US2546658
PMID:23778483
PMID:23887202
PMID:23581274
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|
| notation |
CHEBI:5801
|
| in_subset | |
| inchi |
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
|
| has_related_synonym |
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
oxichloroquine
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
hydroxychloroquine
(+-)-hydroxychloroquine
Polirreumin
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
hidroxicloroquina
7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
hydroxychloroquinum
oxichlorochine
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
NSC4375
See more
See less
|
| id |
CHEBI:5801
|
| fromPubMed |
true
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| textual definition |
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
|
| formula |
C18H26ClN3O
|
| subClassOf | |
| imported from | |
| inchikey |
XXSMGPRMXLTPCZ-UHFFFAOYSA-N
|
| mass |
335.87200
|
| monoisotopicmass |
335.17644
|
| type | |
| smiles |
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
|
| alternative_term |
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
|
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