Preferred Name | Alzheimer's disease | |
Synonyms |
Dementia in Alzheimer's disease (disorder) Alzheimer Disease, Early Onset [X]Dementia in Alzheimer's disease, unspecified (disorder) Alzheimer's Dementia Alzheimer's disease (disorder) Alzheimer's disease Disease, Alzheimer [X]Dementia in Alzheimer's disease Dementia of the Alzheimer's type AD - Alzheimer's disease Alzheimer's Disease Pathway [X]Dementia in Alzheimer's disease, unspecified Senile Dementia ALZHEIMER DIS EARLY ONSET FOCAL ONSET ALZHEIMERS DIS Acute Confusional Senile Dementia Dementias, Presenile Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementias, Senile Alzheimers disease Dementia, Presenile Alzheimer Type Dementia ALZHEIMERS DIS Dementia in Alzheimer's disease, unspecified (disorder) Dementia in Alzheimer's disease Alzheimer Disease, Late Onset LATE ONSET ALZHEIMER DIS Senile Dementia, Alzheimer Type Alzheimer Dementia [X]Dementia in Alzheimer's disease (disorder) Presenile Alzheimer Dementia ALZHEIMER DIS Alzheimer Senile Dementia Alzheimers Dementia Alzheimer's Disease, Focal Onset Primary Senile Degenerative Dementia AD Alzheimers |
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Definitions |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
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ID |
http://www.ebi.ac.uk/efo/EFO_0000249 |
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comment |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
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alternative term |
Dementia in Alzheimer's disease (disorder) Alzheimer Disease, Early Onset [X]Dementia in Alzheimer's disease, unspecified (disorder) Alzheimer's Dementia Alzheimer's disease (disorder) Alzheimer's disease Disease, Alzheimer [X]Dementia in Alzheimer's disease Dementia of the Alzheimer's type AD - Alzheimer's disease Alzheimer's Disease Pathway [X]Dementia in Alzheimer's disease, unspecified Senile Dementia ALZHEIMER DIS EARLY ONSET FOCAL ONSET ALZHEIMERS DIS Acute Confusional Senile Dementia Dementias, Presenile Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementias, Senile Alzheimers disease Dementia, Presenile Alzheimer Type Dementia ALZHEIMERS DIS Dementia in Alzheimer's disease, unspecified (disorder) Dementia in Alzheimer's disease Alzheimer Disease, Late Onset LATE ONSET ALZHEIMER DIS Senile Dementia, Alzheimer Type Alzheimer Dementia [X]Dementia in Alzheimer's disease (disorder) Presenile Alzheimer Dementia ALZHEIMER DIS Alzheimer Senile Dementia Alzheimers Dementia Alzheimer's Disease, Focal Onset Primary Senile Degenerative Dementia AD Alzheimers |
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definition source |
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GeneRIF:12112084 GeneRIF:12408226 GeneRIF:15060098 GeneRIF:16027741 GeneRIF:15053964 GeneRIF:12417379 GeneRIF:9701251 GeneRIF:15030408 GeneRIF:15944016 GeneRIF:14739533 GeneRIF:12127670 GeneRIF:16174740 GeneRIF:15263903 GeneRIF:15804423 GeneRIF:14999081 GeneRIF:14978286 GeneRIF:15255950 GeneRIF:12221172 GeneRIF:16106215 GeneRIF:15034766 GeneRIF:16102903 GeneRIF:15172102 NCIt:C38778 GeneRIF:12809550 GeneRIF:12192622 GeneRIF:12531514 GeneRIF:12807433 GeneRIF:12435432 GeneRIF:15106838 GeneRIF:12882323 GeneRIF:15167696 GeneRIF:15026168 GeneRIF:16116115 GeneRIF:14519529 GeneRIF:11936240 GeneRIF:12149413 GeneRIF:12770689 GeneRIF:12142731 GeneRIF:15708435 GeneRIF:12939405 GeneRIF:15899246 GeneRIF:15082191 GeneRIF:12891359 GeneRIF:12972157 GeneRIF:15728175 GeneRIF:12627474 GeneRIF:12112088 GeneRIF:14717705 GeneRIF:14637088 GeneRIF:11897170 GeneRIF:16111477 GeneRIF:15106853 GeneRIF:16079207 GeneRIF:15068244 GeneRIF:15716413 GeneRIF:12694406 GeneRIF:12605101 GeneRIF:15184629 GeneRIF:12200143 GeneRIF:12702875 GeneRIF:12565837 GeneRIF:15024730 GeneRIF:12960780 GeneRIF:15375590 GeneRIF:15722183 GeneRIF:12070657 GeneRIF:11837744 GeneRIF:14661818 GeneRIF:16130099 DOID:10652 ICD9:331.0 NCIt:C2866 |
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label |
Alzheimer's disease |
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prefixIRI |
efo:EFO_0000249 |
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prefLabel |
Alzheimer's disease |
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see also | ||
term editor |
Tomasz Adamusiak James Malone |
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subClassOf |