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Cell Line Ontology
Last uploaded:
June 20, 2026
| Id | http://purl.obolibrary.org/obo/CL_0000115
http://purl.obolibrary.org/obo/CL_0000115
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|---|---|
| Preferred Name | endothelial cell |
| Definitions |
From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].
An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
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| Synonyms |
endotheliocyte
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. |
|---|---|
| label | endothelial cell
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| prefLabel | endothelial cell
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| comment | From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].
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| prefixIRI | CL:0000115
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| has exact synonym | endotheliocyte
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| present in taxon | |
| has cross-reference |
BTO:0001176
ZFA:0009065
CALOHA:TS-0278
FMA:66772
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