Cell Ontology

Last uploaded: February 13, 2024
Preferred Name

tympanic membrane

Synonyms

Rivinus' membrane

lateral wall of tympanic cavity

paries membranaceus cavi tympani

membranous wall of tympanic cavity

ear drum

eardrum

myrinx

tympanum

Definitions

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

ID

http://purl.obolibrary.org/obo/UBERON_0002364

adjacent to

http://purl.obolibrary.org/obo/UBERON_0004114

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001756

database_cross_reference

EMAPA:19062

Wikipedia:Tympanic_membrane

UMLS:C0041445

VHOG:0001146

SCTID:181180005

XAO:0000212

MESH:D014432

NCIT:C12502

FMA:9595

GAID:870

MA:0000257

definition

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

develops_from

http://purl.obolibrary.org/obo/UBERON_0009213

has part

http://purl.obolibrary.org/obo/UBERON_0010069

http://purl.obolibrary.org/obo/UBERON_0005042

http://purl.obolibrary.org/obo/UBERON_0010070

has_exact_synonym

Rivinus' membrane

lateral wall of tympanic cavity

paries membranaceus cavi tympani

membranous wall of tympanic cavity

ear drum

eardrum

myrinx

has_obo_namespace

uberon

has_related_synonym

tympanum

id

UBERON:0002364

in_subset

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

tympanic membrane

never_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_8459

notation

UBERON:0002364

overlaps

http://purl.obolibrary.org/obo/UBERON_0001691

http://purl.obolibrary.org/obo/UBERON_0001352

part_of

http://purl.obolibrary.org/obo/UBERON_0001756

prefLabel

tympanic membrane

treeView

http://purl.obolibrary.org/obo/UBERON_0001756

http://purl.obolibrary.org/obo/UBERON_0009213

UBPROP_0000001

The thin membrane which closes externally the cavity of the middle ear and is deeply sited at the bottom of the external auditory meatus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]

UBPROP_0000003

In particular, a tympanic membrane was not present in the earliest tetrapods (...). An ear utilizing a tympanic membrane evolved independently at least three times in tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well established][VHOG]

UBPROP_0000011

The tympanic membrane (TM) has three layers, two epithelia provided by the external acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal cleft and pouch, and a mesenchymally derived fibrous stratum

UBPROP_0000012

most AOs consider this part of the middle ear, so we go with this and place it in the middle ear as a border to the external, although it could be considered to overlap the external ear in that it has an EAM layer as part - for this reason we do not consider middle and external ear to be spatially disjoint.

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000094

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0002364 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 FOVT SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 DOID SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 HHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 UPHENO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 MAXO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 FNS-H SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 OBA LOOM
http://purl.jp/bio/4/id/200906037455442262 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LA9368-7 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D014432 MESH LOOM
http://purl.obolibrary.org/obo/MA_0000257 MA LOOM
http://purl.obolibrary.org/obo/OMIT_0015268 OMIT LOOM
http://purl.obolibrary.org/obo/NCIT_C12502 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A09.246.272.702 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU014731 LOINC LOOM
http://purl.obolibrary.org/obo/VHOG_0001146 VHOG LOOM
http://www.projecthalo.com/aura#Tympanic-Membrane AURA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12502 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Tympanic_Membrane CSEO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Tympanic_Membrane SYN LOOM
http://purl.org/obo/owlapi/fma#FMA_9595 BIOMODELS LOOM
http://purl.bioontology.org/ontology/LNC/LP7665-5 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/7N173 RCD LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 FOVT LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 DOID LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 HHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 UPHENO LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 MAXO LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 FNS-H LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014432 RH-MESH LOOM
http://purl.org/sig/ont/fma/fma9595 FMA LOOM
http://id.nlm.nih.gov/mesh/D014432 MDM LOOM
http://purl.jp/bio/11/meo/MEO_0000800 MEO LOOM
http://radlex.org/RID/RID10100 RADLEX LOOM
http://purl.obolibrary.org/obo/EMAPA_19062 EMAPA LOOM