Cell Ontology

Last uploaded: June 8, 2026
Id http://purl.obolibrary.org/obo/PR_000001810
http://purl.obolibrary.org/obo/PR_000001810
Preferred Name

CSF-1/PDGF receptor-type tyrosine-protein kinase

Definitions
Category=family. A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.
Type http://www.w3.org/2002/07/owl#Class
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