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Cell Ontology
Last uploaded:
March 26, 2026
| Id | http://purl.obolibrary.org/obo/PR_000001012
http://purl.obolibrary.org/obo/PR_000001012
|
|---|---|
| Preferred Name | integrin alpha-M |
| Definitions |
Category=gene. Requested by=CL.
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.
|
| Synonyms |
CR-3 alpha chain
CD11 antigen-like family member B
neutrophil adherence receptor
cell surface glycoprotein MAC-1 subunit alpha
leukocyte adhesion receptor MO1
CD11b
ITGAM
CD11B
CR3A
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. |
|---|---|
| label | integrin alpha-M
|
| comment | Category=gene. Requested by=CL.
|
| prefLabel | integrin alpha-M
|
| database_cross_reference | IUPHARobj:2452
|
| notation | PR:000001012
|
| has_related_synonym |
CD11B
CR3A
|
| id | PR:000001012
|
| has_obo_namespace | protein
|
| subClassOf | |
| type | |
| has_exact_synonym |
CR-3 alpha chain
CD11 antigen-like family member B
neutrophil adherence receptor
cell surface glycoprotein MAC-1 subunit alpha
leukocyte adhesion receptor MO1
CD11b
ITGAM
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