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Cell Ontology
Last uploaded:
March 26, 2026
| Id | http://purl.obolibrary.org/obo/CL_0011115
http://purl.obolibrary.org/obo/CL_0011115
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| Preferred Name | precursor cell |
| Definitions |
Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.
A cell that, by division or terminal differentiation, can give rise to other cell types.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cell that, by division or terminal differentiation, can give rise to other cell types. |
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| prefLabel | precursor cell
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| label | precursor cell
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| comment | Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.
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| description | Precursor cells represent an intermediate stage between an undifferentiated stem cell and a fully specialized cell.
Possessing the ability to differentiate into one or multiple specialized cell types, precursor cells exhibit partial stem cell characteristics. This differentiation is vital for various aspects of biological development and maintenance. Neural precursor cells, for example, can give rise to neurons, astrocytes, and oligodendrocytes, while hematopoietic precursor cells can transform into different blood cell types. This orchestrated process aligns with the body's metabolic activities, ensuring the production of the right cell types in response to physiological needs.
Moreover, the study of precursor cells has become a promising field in regenerative medicine and cellular therapies. However, it's essential to note that precursor cells have a more limited self-renewal capacity compared to stem cells, and once they start differentiating along a specific cell lineage, the process is often irreversible.
(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)
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| prefixIRI | CL:0011115
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