loading...| Preferred Name |
Langerhans cell |
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| Synonyms |
LC |
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| Definitions |
Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. |
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| ID |
http://purl.obolibrary.org/obo/CL_0000453 |
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| comment |
Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. |
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| capable of | ||
| capable of part of | ||
| database_cross_reference |
MESH:D007801 CALOHA:TS-2375 BTO:0000705 FMA:63072 |
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| definition |
Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. |
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| develops_from | ||
| functionally related to | ||
| has part | ||
| has plasma membrane part | ||
| has_exact_synonym |
LC |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
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| label |
Langerhans cell |
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| overlaps | ||
| prefixIRI |
CL:0000453 |
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| prefLabel |
Langerhans cell |
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| present in taxon | ||
| treeView | ||
| subClassOf |