Coronavirus Infectious Disease Ontology

Last uploaded: February 16, 2024
Id http://purl.obolibrary.org/obo/PR_000030035
http://purl.obolibrary.org/obo/PR_000030035
Preferred Name

G-protein coupled receptor
Definitions
Category=family. Classification based on GRAFS system. [PMID:12761335] A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.
Synonyms
fam:GPCR
7TM receptor
seven-transmembrane receptor
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
G-protein coupled receptor
label
G-protein coupled receptor
comment
Category=family. Classification based on GRAFS system. [PMID:12761335]
has exact synonym
fam:GPCR
has_broad_synonym
7TM receptor
seven-transmembrane receptor
textual definition
A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.
has_obo_namespace
protein
notation
PR:000030035
imported from
type
subClassOf
database_cross_reference
IUPHARfam:694
id
PR:000030035
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