Coronavirus Infectious Disease Ontology

Last uploaded: February 16, 2024
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Preferred Name

map kinase p38
Synonyms

fam:MAPKp38
Definitions

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (environmental stress, pro-inflammatory cytokines and lipopolysaccharide) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. Category=family.
ID

http://purl.obolibrary.org/obo/PR_000003106
comment

Category=family.
alternative term

fam:MAPKp38
database_cross_reference

PIRSF:PIRSF500943
has exact synonym

fam:MAPKp38
has_obo_namespace

protein
id

PR:000003106
imported from

http://purl.obolibrary.org/obo/pr.owl
label

map kinase p38
notation

PR:000003106
prefLabel

map kinase p38
textual definition

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (environmental stress, pro-inflammatory cytokines and lipopolysaccharide) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.
subClassOf

http://purl.obolibrary.org/obo/PR_000000001
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