Coronavirus Infectious Disease Ontology

Last uploaded: February 16, 2024
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Preferred Name

Cardiac Glycosides [Chemical/Ingredient]
Synonyms
ID

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000008157
code

C26678
Display_Name

Cardiac Glycosides
imported from

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl
label

Cardiac Glycosides [Chemical/Ingredient]
MeSH_CUI

M0003451
MeSH_Definition

Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
MeSH_DUI

D002301
MeSH_Name

Cardiac Glycosides
NUI

N0000008157
prefixIRI

NDF-RT:N0000008157
prefLabel

Cardiac Glycosides [Chemical/Ingredient]
RxNorm_CUI

2079
Synonym

Cardiotonic Steroids
UMLS_CUI

C0007158
subClassOf

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007897

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000008140
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