CHEBI Integrated Role Ontology

Last uploaded: December 17, 2019
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Preferred Name

abnormal humoral immune response
Synonyms

humoral immune response dysfunction

antibody-mediated immune response abnormalities
Definitions

any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination
ID

http://purl.obolibrary.org/obo/MP_0001800
definition

any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination
has_exact_synonym

humoral immune response dysfunction

antibody-mediated immune response abnormalities
has_obo_namespace

MPheno.ontology
id

MP:0001800
label

abnormal humoral immune response
notation

MP:0001800
prefLabel

abnormal humoral immune response
subClassOf

http://purl.obolibrary.org/obo/MP_0001790
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