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CHEBI Integrated Role Ontology
Last uploaded:
December 17, 2019
| Acronym | CHIRO |
| Visibility | Public |
| Description | CHEBI provides a distinct role hierarchy. Chemicals in the structural hierarchy are connected via a 'has role' relation. CHIRO provides links from these roles to useful other classes in other ontologies. This will allow direct connection between chemical structures (small molecules, drugs) and what they do. This could be formalized using 'capable of', in the same way Uberon and the Cell Ontology link structures to processes. |
| Status | Production |
| Format | OWL |
| Contact | Nicole Vasilevsky, vasilevs@ohsu.edu |
| Groups | OBO Foundry |
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| Id | http://purl.obolibrary.org/obo/CHEBI_35664
http://purl.obolibrary.org/obo/CHEBI_35664
|
|---|---|
| Preferred Name | hydroxymethylglutaryl-CoA reductase inhibitor |
| Definitions |
A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis.
|
| Synonyms |
HMG-CoA reductase inhibitor
hydroxymethylglutaryl-CoA reductase inhibitors
statin
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. |
|---|---|
| label | hydroxymethylglutaryl-CoA reductase inhibitor
|
| prefLabel | hydroxymethylglutaryl-CoA reductase inhibitor
|
| database_cross_reference | Wikipedia:Statin
|
| notation | CHEBI:35664
|
| has_related_synonym |
HMG-CoA reductase inhibitor
hydroxymethylglutaryl-CoA reductase inhibitors
statin
|
| id | CHEBI:35664
|
| has_obo_namespace | chebi_ontology
|
| subClassOf | |
| type |
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