Preferred Name |
verapamil |
|
Synonyms |
Verapamil rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile verapamilum verapamilo verapamil |
|
Definitions |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_9948 |
|
charge |
0 |
|
database_cross_reference |
Beilstein:2825000 PMID:24532601 KEGG:D02356 DrugBank:DB00661 PMID:25650380 PMID:14681337 PMID:25331694 PMID:17525564 PMID:8861548 PMID:26504804 HMDB:HMDB0001850 PMID:17724247 Reaxys:2825000 PMID:18337499 PMID:19125880 PMID:26553277 PMID:26046259 PMID:11142488 PMID:11389609 PMID:12454681 PMID:26567612 PMID:25968157 PMID:25297337 PMID:11975770 PMID:11454724 CAS:52-53-9 PMID:16545584 PMID:18093581 Wikipedia:Verapamil PMID:24577794 KEGG:C07188 |
|
definition |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
|
formula |
C27H38N2O4 |
|
has part | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_77745 http://purl.obolibrary.org/obo/CHEBI_62872 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_77748 http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_77747 |
|
has_exact_synonym |
Verapamil rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
verapamilum verapamilo verapamil |
|
id |
CHEBI:9948 |
|
in_subset | ||
label |
verapamil |
|
mass |
454.60160 |
|
monoisotopicmass |
454.28316 |
|
notation |
CHEBI:9948 |
|
prefLabel |
verapamil |
|
treeView | ||
subClassOf |