Preferred Name

fluvastatin

Synonyms

rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

fluvastatinum

rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid

fluvastatina

(+-)-fluvastatin

fluvastatine

erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid

fluvastatin

(6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

rac-(3R,5S)-fluvastatin

Cranoc

Definitions

A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia.

ID

http://purl.obolibrary.org/obo/CHEBI_38561

charge

0

database_cross_reference

KEGG:D07983

Beilstein:9168031

PMID:18936176

DrugBank:DB01095

PMID:23846727

Patent:WO8402131

CAS:93957-54-1

PMID:11273020

KEGG:C07014

Wikipedia:Fluvastatin

PMID:18413661

PMID:12147804

PMID:23212095

PMID:18452779

Patent:US4739073

PMID:18410471

definition

A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia.

formula

C24H26FNO4

has part

http://purl.obolibrary.org/obo/CHEBI_38565

http://purl.obolibrary.org/obo/CHEBI_5136

has role

http://purl.obolibrary.org/obo/CHEBI_35821

http://purl.obolibrary.org/obo/CHEBI_77255

has_exact_synonym

rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

has_obo_namespace

chebi_ontology

has_related_synonym

fluvastatinum

rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid

fluvastatina

(+-)-fluvastatin

fluvastatine

erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid

fluvastatin

(6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

rac-(3R,5S)-fluvastatin

Cranoc

id

CHEBI:38561

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1

inchikey

FJLGEFLZQAZZCD-JUFISIKESA-N

label

fluvastatin

mass

411.467

monoisotopicmass

411.18459

notation

CHEBI:38561

prefLabel

fluvastatin

smiles

C1(=CC=C(C=C1)C=2C=3C(N(C2/C=C/[C@@H](C[C@@H](CC(O)=O)O)O)C(C)C)=CC=CC3)F

treeView

http://purl.obolibrary.org/obo/CHEBI_87635

http://purl.obolibrary.org/obo/CHEBI_60911

subClassOf

http://purl.obolibrary.org/obo/CHEBI_87635

http://purl.obolibrary.org/obo/CHEBI_60911

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http://purl.obolibrary.org/obo/CHEBI_38561 PDRO SAME_URI
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http://purl.obolibrary.org/obo/CHEBI_38561 BERO SAME_URI
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http://purl.obolibrary.org/obo/CHEBI_38561 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_38561 DIDEO SAME_URI
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http://purl.obolibrary.org/obo/CHEBI_38561 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_38561 DIDEO LOOM
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http://sbmi.uth.tmc.edu/ontology/ochv#C0082608 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15374 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387585004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D000077340 MESH LOOM
http://purl.obolibrary.org/obo/DRON_00012123 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_38562 BIOMODELS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C065180 RH-MESH LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02123 MIO LOOM
https://go.drugbank.com/drugs/DB01095 MDM LOOM
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http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000021914 OCVDAE LOOM
http://purl.bioontology.org/ontology/VANDF/4023909 VANDF LOOM
http://scai.fraunhofer.de/AlzheimerOntology#fluvastatin ADO LOOM
http://purl.obolibrary.org/obo/HIO_0000304 HIO LOOM
http://purl.bioontology.org/ontology/SNMI/C-80830 SNMI LOOM