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Chemical Entities of Biological Interest Ontology
Last uploaded:
November 5, 2024
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| Preferred Name | memantine | |
| Synonyms |
memantine memantinum 1,3-Dimethyl-5-adamantanamine 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine 1-Amino-3,5-dimethyladamantane 3,5-Dimethyl-1-adamantanamine 3,5-Dimethyl-1-aminoadamantane memantina 3,5-dimethyladamantan-1-amine |
|
| Definitions |
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_64312 |
|
| charge |
0
|
|
| database_cross_reference |
KEGG:D08174 PMID:22030128 CAS:19982-08-2 Drug_Central:1679 LINCS:LSM-5154 PMID:22290557 PMID:22311362 PMID:22134197 KEGG:C13736 PMID:21953515 Patent:US2011282100 PMID:22392787 PMID:22245025 PMID:22327556 Reaxys:2075983 PMID:22414570 PMID:21955815 PMID:22248638 PMID:22300835 PMID:22329473 PMID:22425751 PMID:22297273 PMID:20104942 DrugBank:DB01043 Wikipedia:Memantine
|
|
| definition |
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
|
|
| formula |
C12H21N
|
|
| has parent hydride | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_48560 http://purl.obolibrary.org/obo/CHEBI_63726 http://purl.obolibrary.org/obo/CHEBI_35469 |
|
| has_alternative_id |
CHEBI:34832
|
|
| has_exact_synonym |
3,5-dimethyladamantan-1-amine
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
memantine memantinum 1,3-Dimethyl-5-adamantanamine 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine 1-Amino-3,5-dimethyladamantane 3,5-Dimethyl-1-adamantanamine 3,5-Dimethyl-1-aminoadamantane memantina
|
|
| id |
CHEBI:64312
|
|
| in_subset | ||
| inchi |
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
|
|
| inchikey |
BUGYDGFZZOZRHP-UHFFFAOYSA-N
|
|
| is conjugate base of | ||
| label |
memantine
|
|
| mass |
179.30180
|
|
| monoisotopicmass |
179.16740
|
|
| notation |
CHEBI:64312
|
|
| prefLabel |
memantine
|
|
| smiles |
CC12CC3CC(C)(C1)CC(N)(C3)C2
|
|
| treeView | ||
| subClassOf |
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